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  1. Article

    Open Access

    A new mode of SAM domain mediated oligomerization observed in the CASKIN2 neuronal scaffolding protein

    CASKIN2 is a homolog of CASKIN1, a scaffolding protein that participates in a signaling network with CASK (calcium/calmodulin-dependent serine kinase). Despite a high level of homology between CASKIN2 and CASK...

    Ekaterina Smirnova, Jamie J. Kwan, Ryan Siu, **n Gao… in Cell Communication and Signaling (2016)

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    Article

    Molecular recognition of p53 and MDM2 by USP7/HAUSP

    The ubiquitin-specific protease, USP7, has key roles in the p53 pathway whereby it stabilizes both p53 and MDM2. We show that the N-terminal domain of USP7 binds two closely spaced 4-residue sites in both p53 ...

    Yi Sheng, Vivian Saridakis, Feroz Sarkari… in Nature Structural & Molecular Biology (2006)

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    Article

    Structural proteomics of an archaeon

    A set of 424 nonmembrane proteins from Methanobacterium thermoautotrophicum were cloned, expressed and purified for structural studies. Of these, ∼20% were found to be suitable candidates for X-ray crystallograp...

    Dinesh Christendat, Adelinda Yee, Akil Dharamsi, Yuval Kluger… in Nature Structural Biology (2000)