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MEN1 mutations and potentially MEN1-targeting miRNAs are responsible for menin deficiency in sporadic and MEN1 syndrome-associated primary hyperparathyroidism

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  1. Article

    Open Access

    Cell facilitation promotes growth and survival under drug pressure in breast cancer

    The interplay of positive and negative interactions between drug-sensitive and resistant cells influences the effectiveness of treatment in heterogeneous cancer cell populations. Here, we study interactions be...

    Rena Emond, Jason I. Griffiths, Vince Kornél Grolmusz, Aritro Nath… in Nature Communications (2023)

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  2. Article

    Open Access

    Exploiting collateral sensitivity controls growth of mixed culture of sensitive and resistant cells and decreases selection for resistant cells in a cell line model

    CDK4/6 inhibitors such as ribociclib are becoming widely used targeted therapies in hormone-receptor-positive (HR+) human epidermal growth factor receptor 2-negative (HER2−) breast cancer. However, cancers can...

    Vince Kornél Grolmusz, **feng Chen, Rena Emond… in Cancer Cell International (2020)

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  3. Article

    Open Access

    True MEN1 or phenocopy? Evidence for geno-phenotypic correlations in MEN1 syndrome

    Multiple endocrine neoplasia type 1 is a rare tumor syndrome caused by germline mutations of MEN1 gene. Phenotype varies widely, and no definitive correlation with the genotype has been observed. Mutation-negativ...

    Annamária Kövesdi, Miklós Tóth, Henriett Butz, Nikolette Szücs, Beatrix Sármán… in Endocrine (2019)

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  4. Article

    Open Access

    Fluorescence activated cell sorting followed by small RNA sequencing reveals stable microRNA expression during cell cycle progression

    Previously, drug-based synchronization procedures were used for characterizing the cell cycle dependent transcriptional program. However, these synchronization methods result in growth imbalance and alteration...

    Vince Kornél Grolmusz, Eszter Angéla Tóth, Kornélia Baghy, István Likó… in BMC Genomics (2016)

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