3 Result(s)
within
Vinay K. Mittal
Biomedicine
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Article
Open AccessDe novo assembly and characterization of breast cancer transcriptomes identifies large numbers of novel fusion-gene transcripts of potential functional significance
Gene-fusion or chimeric transcripts have been implicated in the onset and progression of a variety of cancers. Massively parallel RNA sequencing (RNA-Seq) of the cellular transcriptome is a promising approach ...
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Article
Open AccessIntegrated sequence and expression analysis of ovarian cancer structural variants underscores the importance of gene fusion regulation
Genomic rearrangements or structural variants (SVs) are one of the most common classes of mutations in cancer.
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Article
Open AccessCharacterization and potential functional significance of human-chimpanzee large INDEL variation
Although humans and chimpanzees have accumulated significant differences in a number of phenotypic traits since diverging from a common ancestor about six million years ago, their genomes are more than 98.5% i...
