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Article
Effect of short-term exposure to high-altitude hypoxic climate on feed-intake, blood glucose level and physiological responses of native and non-native goat
The exposure to high altitude and cold stress poses challenges in maintaining normal physiological standards and body homeostasis in non-native animals. To enhance our understanding of the physiology of native...
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Article
Open AccessEcotoxicology of magnesium-based explosive: impact on animal and human food chain
The previous few decades have seen widespread environmental exposure to munitions and explosives systems in and around war and weapon testing ranges. Most contemporary warheads use explosives to launch metal s...
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Article
Open AccessHigh-altitude and low-altitude adapted chicken gut-microbes have different functional diversity
Recently, there has been considerable interest in the functions of gut microbiota in broiler chickens in relation to their use as feed additives. However, the gut-microbiota of chickens reared at different alt...
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Article
Open AccessEvaluation of physico-chemical and heavy metals status in irrigation, stagnant, and Indus River water at the trans-Himalayan region
The water quality of various resources is changing everywhere, including the high-altitude region, which may have adverse health effects on animals and the human population. So far, not much study has been con...
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Chapter
Pineal Gland Physiology and Aging-Related Alterations in the Circadian Timing System
For the last few decades, multiple research groups have studied the various processes, mechanisms, and regulations that can be manipulated to slow down the aging process in both animals and humans. Melatonin, ...
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Article
Open AccessSelection of species specific panel of reference genes in peripheral blood mononuclear cells of native livestock species adapted to trans-Himalayan region of Leh-Ladakh
The identification of appropriate references genes is an integral component of any gene expression-based study for getting accuracy and reliability in data interpretation. In this study, we evaluated the expre...
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Article
Health Risk Assessment of Heavy Metals Due to Wheat, Cabbage, and Spinach Consumption at Cold-Arid High Altitude Region
Soil and water from the trans-Himalayan high-altitude region contain high concentrations of various heavy metals. Vegetables and cereals such as cabbage, spinach, and wheat are most prone to heavy metal accumu...
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Article
Open AccessHydrochemical and quality assessment of irrigation water at the trans-himalayan high-altitude regions of Leh, Ladakh, India
A total of seventy irrigation water samples were collected from Leh, Ladakh, India, to determine their hydrochemistry profile and water quality for irrigation purposes. Water quality indices such as total hard...
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Article
Health Risk Assessment of Heavy Metals Through Cow Milk Consumption in Trans-Himalayan High-Altitude Region
Consumption of heavy metals contaminated dairy milk may affect human health. No such studies have been carried out at the high-altitude region to assess the human health risk after consuming dairy milk. To thi...
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Article
Open AccessMorphometric, haematological and physio-biochemical characterization of Bactrian (Camelus bactrianus) camel at high altitude
Biochemical and haematological parameters have not been determined in Bactrian camels kept at high altitude. Therefore, this study was undertaken to characterise different physiological, haematological, bioche...
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Article
Chemometric Analysis of Antioxidant and Mineral Elements in Colostrum of Native and Non-native Goat Breeds to Hypoxic Conditions at High Altitude
Colostrum of goat is a well-known nutritional source of animal product, which is attributed to innumerable nutritional properties. To enrich nutritional resources for understanding various nutritional values o...
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Article
Open AccessA review on water quality and dairy cattle health: a special emphasis on high-altitude region
Water is the wonder of nature which is an essential source of nutrient for all forms of life. It helps in proper digestion, energy metabolism, transport of nutrients and metabolites, cellular functions, and ex...
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Article
Antibiofilm potential of Seabuckthorn silver nanoparticles (SBT@AgNPs) against Pseudomonas aeruginosa
In era of antibiotic resistance, antibacterial silver nanoparticles are considered as potential alternative therapeutic agent to combat drug resistant pathogens. The aim of present study was to evaluate the an...
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Article
Open AccessUtility of multivariate statistical analysis to identify factors contributing river water quality in two different seasons in cold-arid high-altitude region of Leh-Ladakh, India
Monitoring water quality of surface water resources is the key concern in determining the potable water quality in high-altitude region. Therefore, there is a need to evaluate different parameters affecting wa...
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Sea Buckthorn and Apricot Based Nutraceuticals
A high-altitude environment is characterized by hypobaric hypoxia, extreme temperature variation, low humidity, intense ultraviolet radiation, low rainfall, and high wind velocity. These types of extreme clima...
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Article
Open AccessTranscriptome Analysis of Circulating PBMCs to Understand Mechanism of High Altitude Adaptation in Native Cattle of Ladakh Region
Ladakhi cattle is native population of Leh and Ladakh region and constantly exposed to hypobaric hypoxia over many generations. In present study, transcriptome signatures of cattle from Ladakh region (~5500 m)...
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Article
Open AccessHippophae rhamnoides as novel phytogenic feed additive for broiler chickens at high altitude cold desert
Extremes of climate and hypobaric hypoxia cause poor growth performance in broiler chickens at high altitude. The present study examined the potential of Hippophae rhamnoides extract as phytogenic feed additive f...
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Article
Open AccessStudies on the growth performance of different broiler strains at high altitude and evaluation of probiotic effect on their survivability
Identification of appropriate breeds of broilers and development of new feed additives is required for the development of poultry industry at high altitude. Therefore, this experiment was conducted first to id...
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Article
Melatonin Antioxidative Defense: Therapeutical Implications for Aging and Neurodegenerative Processes
The pineal product melatonin has remarkable antioxidant properties. It is secreted during darkness and plays a key role in various physiological responses including regulation of circadian rhythms, sleep homeo...
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Article
Evaluation of blood antioxidant defense and apoptosis in peripheral lymphocytes on exogenous administration of pineal proteins and melatonin in rats
In view of the significant health impact of oxidative stress and apoptosis dysfunction, and further, because of suggestions that administration of antioxidants might reduce apoptosis rate through up-regulation...
