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Article
Cardiovascular and renal outcomes in patients with atrial fibrillation and stage 4–5 chronic kidney disease receiving direct oral anticoagulants: a multicenter retrospective cohort study
The role of direct oral anticoagulants (DOAC) in patients with atrial fibrillation (AF) and stage 4–5 chronic kidney disease (CKD) is controversial. Electronic medical records from 2012 to 2021 were retrieved ...
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Article
Prognostic Effects of Liver Fibrosis and Steatosis Determined Using Transient Elastography in Patients with Chronic Hepatitis B or C
The prognostic effects of liver fibrosis and steatosis in patients with chronic hepatitis B or C are unclear. We investigated the prognostic effects of liver fibrosis and steatosis determined through transient...
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Article
Open AccessSex differences in utilisation of extracorporeal membrane oxygenation support and outcomes in Taiwan
The impact of sex-related differences in patients receiving extracorporeal membrane oxygenation support (ECMO) support is still inconclusive. This population-based study aimed to investigate sex differences in...
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Article
Open AccessThe cardiovascular and renal effects of glucagon-like peptide 1 receptor agonists in patients with advanced diabetic kidney disease
To determine whether glucagon-like peptide 1 receptor agonists (GLP-1RAs) have cardiovascular and renal protective effects in patients with advanced diabetic kidney disease (DKD) with an estimated glomerular f...
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Article
Open AccessSurgical volume and outcomes of surgical ablation for atrial fibrillation: a nationwide population-based cohort study
Atrial fibrillation is the most common cardiac arrythmia and causes many complications. Sinus rhythm restoration could reduce late mortality of atrial fibrillation patients. The Maze procedure is the gold stan...
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Article
Risk of major bleeding associated with concomitant use of anticancer drugs and direct oral anticoagulant in patients with cancer and atrial fibrillation
This study evaluated the risk of major bleeding associated with concomitant use of direct oral anticoagulant (DOAC) and anticancer drugs (ACDs), which share metabolic pathways, in patients with atrial fibrilla...
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Article
Open AccessEffects of dexmedetomidine on surgery for type A acute aortic dissection outcome
No study has evaluated the effect of dexmedetomidine in patients who received surgery for type A aortic dissection. This is the first study to evaluate the effect of dexmedetomidine in aortic dissection patien...
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Article
Open AccessA validation study comparing existing prediction models of acute kidney injury in patients with acute heart failure
Acute kidney injury (AKI) is a common complication in acute heart failure (AHF) and is associated with prolonged hospitalization and increased mortality. The aim of this study was to externally validate existi...
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Article
Atrial fibrillation and associated outcomes in patients with peritoneal dialysis and hemodialysis: a 14-year nationwide population-based study
Patients with end-stage renal disease (ESRD) undergoing dialysis have increased risks of atrial fibrillation (AF).
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Article
Incidence and consequences of resuming oral anticoagulant therapy following hematuria and risks of ischemic stroke and major bleeding in patients with atrial fibrillation
Following hematuria, it is uncertain to what extent a vitamin K antagonist (VKA) or non-VKA oral anticoagulant (NOAC) is resumed, and the risks of ischemic stroke/systemic embolism and major bleeding associate...
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Article
Open AccessSodium-glucose cotransporter 2 inhibitor versus metformin as first-line therapy in patients with type 2 diabetes mellitus: a multi-institution database study
Sodium-glucose co-transporter 2 inhibitors (SGLT2i) has shown evidence of cardiovascular benefit in patients with type 2 diabetes mellitus (T2DM). Currently metformin is the guideline-recommended first-line tr...
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Article
Open AccessAssociation between initial dialytic modalities and the risks of mortality, infection death, and cardiovascular events: A nationwide population-based cohort study
To date, few studies have been conducted to pairwise compare the prognosis of peritoneal dialysis (PD), unplanned PD, and unplanned hemodialysis (HD). We analyzed longitudinal data from Taiwan’s National Healt...
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Article
Open AccessLong-term Outcome of Neurological Complications after Infective Endocarditis
Severe neurological complications following infective endocarditis remain a major problem with high mortality rate. The long-term neurological consequences following infective endocarditis remain uncertain. Ot...
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Article
Open AccessAnalysis of survival after initiation of continuous renal replacement therapy in patients with extracorporeal membrane oxygenation
No study has specifically investigated the duration of continuous renal replacement therapy (CRRT) in patients who experienced acute kidney injury during extracorporeal membrane oxygenation (ECMO) support. How...
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Article
Effectiveness and safety of non-vitamin-K antagonist oral anticoagulants versus warfarin in atrial fibrillation patients with thrombocytopenia
Patients with thrombocytopenia were excluded from major clinical trials that investigated non-vitamin-K antagonist oral anticoagulants (NOACs) for stroke prevention in atrial fibrillation (AF). The aim of this...
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Article
Serum asprosin levels and bariatric surgery outcomes in obese adults
Asprosin is a novel fasting-induced glucogenic and orexigenic protein hormone. The clinical function of asprosin in obesity is currently unknown. This study investigated the association between asprosin abunda...
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Article
Open AccessRed cell distribution width associated with adverse cardiovascular outcomes in patients with chronic kidney disease
Recent studies have demonstrated that red cell distribution width (RDW) is associated with cardiovascular (CV) events and mortality. Patients with chronic kidney disease (CKD) are often anemic and have high RD...
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Article
Open AccessPhenotypic expressions of hereditary Transthyretin Ala97Ser related Amyloidosis (ATTR) in Taiwanese
The disease course and early signs specific to ATTR Ala97Ser, the most common endemic mutation in Taiwan, have not been well described. Since new medications can slow down the rate of disease progression, the ...