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Article
Inter-country variability over time in the mortality of mechanically ventilated patients
Variations in clinical characteristics and management and in the mortality of mechanically ventilated patients have not been sufficiently evaluated. We hypothesized that mortality shows a variability associate...
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Article
Open AccessClinical interval and diagnostic characteristics in a cohort of bladder cancer patients in Spain: a multicenter observational study
We performed a cohort study in seven hospitals in Spain to determine the clinical characteristics of incident patients with bladder cancer, the diagnostic process, and the conditions that might affect health c...
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Article
Impact of sedation and analgesia during noninvasive positive pressure ventilation on outcome: a marginal structural model causal analysis
There are limited data available about the role of sedation and analgesia during noninvasive positive pressure ventilation (NPPV). The objective of study was to estimate the effect of analgesic or sedative dru...
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Article
Open AccessClinical intervals and diagnostic characteristics in a cohort of prostate cancer patients in Spain: a multicentre observational study
Little is known about the healthcare process for patients with prostate cancer, mainly because hospital-based data are not routinely published. The main objective of this study was to determine the clinical ch...
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Article
Open AccessWillingness to pay for a quality-adjusted life year: an evaluation of attitudes towards risk and preferences
This paper examines the Willingness to Pay (WTP) for a quality-adjusted life year (QALY) expressed by people who attended the healthcare system as well as the association of attitude towards risk and other per...
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Article
Disc degeneration and chronic low back pain: an association which becomes nonsignificant when endplate changes and disc contour are taken into account
The objective of this study was to assess the association between severe disc degeneration (DD) and low back pain (LBP).
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Chapter
An Introduction to Diagnostic Meta-analysis
Systematic review, and its corresponding statistical analysis, is becoming popular in the literature to assess the diagnostic accuracy of a test. When correctly performed, this research methodology provides fu...
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Article
Magnetic resonance imaging in the preoperative assessment of patients with primary breast cancer: systematic review of diagnostic accuracy and meta-analysis
To estimate the diagnostic accuracy of magnetic resonance imaging (MRI) in detecting additional lesions and contralateral cancer not identified using conventional imaging in primary breast cancer.
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Article
Open AccessHuman papillomavirus genotype distribution in Madrid and correlation with cytological data
Cervical cancer is the second most common cancer in women worldwide. Infection with certain human papillomavirus (HPV) genotypes is the most important risk factor associated with cervical cancer. This study an...
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Article
Open AccessMinimum detectable and minimal clinically important changes for pain in patients with nonspecific neck pain
The minimal detectable change (MDC) and the minimal clinically important changes (MCIC) have been explored for nonspecific low back pain patients and are similar across different cultural settings. No data on ...
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Article
Open AccessPsychometric characteristics of the Spanish version of instruments to measure neck pain disability
The NDI, COM and NPQ are evaluation instruments for disability due to NP. There was no Spanish version of NDI or COM for which psychometric characteristics were known. The objectives of this study were to tran...
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Article
The social tariff of EQ-5D is not adequate to assess quality of life in patients with low back pain
We compared the quality of life perceived by patients with non-specific low back pain with that predicted by the social tariff of the Spanish version of EQ-5D questionnaire.
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Article
Open AccessMeta-DiSc: a software for meta-analysis of test accuracy data
Systematic reviews and meta-analyses of test accuracy studies are increasingly being recognised as central in guiding clinical practice. However, there is currently no dedicated and comprehensive software for ...
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Article
Presentation and prognosis of gastric cancer in patients aged 80 years and older
The aim of this study was to analyze the characteristics of the presentation and prognosis of patients aged ≥ 80 who were diagnosed with gastric adenocarcinoma. We have used a retrospective cohort study of 233...
