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    Article

    Genetic architecture of subcortical brain structures in 38,851 individuals

    Subcortical brain structures are integral to motion, consciousness, emotions and learning. We identified common genetic variation related to the volumes of the nucleus accumbens, amygdala, brainstem, caudate n...

    Claudia L. Satizabal, Hieab H. H. Adams, Derrek P. Hibar in Nature Genetics (2019)

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    Novel genetic loci underlying human intracranial volume identified through genome-wide association

    In a GWAS study of 32,438 adults, the authors discovered five novel loci for intracranial volume and confirmed two known signals. Variants for intracranial volume were also related to childhood and adult cogni...

    Hieab H H Adams, Derrek P Hibar, Vincent Chouraki, Jason L Stein in Nature Neuroscience (2016)

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    Neural correlates of genetically abnormal social cognition in Williams syndrome

    Williams-Beuren syndrome (WBS), caused by a microdeletion of approximately 21 genes on chromosome 7q11.23, is characterized by unique hypersociability combined with increased non-social anxiety. Using function...

    Andreas Meyer-Lindenberg, Ahmad R Hariri, Karen E Munoz in Nature Neuroscience (2005)

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    5-HTTLPR polymorphism impacts human cingulate-amygdala interactions: a genetic susceptibility mechanism for depression

    Carriers of the short allele of a functional 5′ promoter polymorphism of the serotonin transporter gene have increased anxiety-related temperamental traits, increased amygdala reactivity and elevated risk of d...

    Lukas Pezawas, Andreas Meyer-Lindenberg, Emily M Drabant in Nature Neuroscience (2005)