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  1. Article

    Open Access

    4-3-oxo-5β-reductase deficiency: favorable outcome in 16 patients treated with cholic acid

    Oral cholic acid therapy is an effective therapy in children with primary bile acid synthesis deficiencies. Most reported patients with this treatment have 3β-hydroxy-Δ5-C27-steroid oxidoreductase deficiency. The...

    Antoine Gardin, Mathias Ruiz, Jan Beime, Mara Cananzi in Orphanet Journal of Rare Diseases (2023)

  2. Article

    Open Access

    Exclusive enteral nutrition with concomitant early thiopurine use was effective in maintaining steroid-free remission in a Southeast Asian cohort of children with Crohn’s disease

    Exclusive enteral nutrition (EEN) is as effective as corticosteroids in inducing remission in children with Crohn’s disease (CD). However, over 50% of these children relapse by 12 months of diagnosis. Thiopuri...

    Christina Ong, Poh Ting Lim, Veena Logarajah, Maria Janelle Liwanag in BMC Gastroenterology (2018)