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Article
Investigating the reference domain influence in personalised models of cardiac mechanics
A major concern in personalised models of heart mechanics is the unknown zero-pressure domain, a prerequisite for accurately predicting cardiac biomechanics. As the reference configuration cannot be captured b...
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Article
Open AccessDecompressive craniectomy of post-traumatic brain injury: an in silico modelling approach for intracranial hypertension management
Traumatic brain injury (TBI) causes brain edema that induces increased intracranial pressure and decreased cerebral perfusion. Decompressive craniectomy has been recommended as a surgical procedure for the man...
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Article
Multiscale modelling of solid tumour growth: the effect of collagen micromechanics
Here we introduce a model of solid tumour growth coupled with a multiscale biomechanical description of the tumour microenvironment, which facilitates the explicit simulation of fibre–fibre and tumour–fibre in...
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Chapter and Conference Paper
Breast Conserving Surgery Outcome Prediction: A Patient-Specific, Integrated Multi-modal Imaging and Mechano-Biological Modelling Framework
Patient-specific surgical predictions of Breast Conserving Therapy, through mechano-biological simulations, could inform the shared decision making process between clinicians and patients by enabling the impac...
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Article
An Inverse Finite Element u/p-Formulation to Predict the Unloaded State of In Vivo Biological Soft Tissues
Physically realistic patient-specific biomechanical modelling is of paramount importance for many medical applications, where the geometry of tissues or organs is usually constructed from in vivo images. However,...
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Article
Open AccessSymmetric Biomechanically Guided Prone-to-Supine Breast Image Registration
Prone-to-supine breast image registration has potential application in the fields of surgical and radiotherapy planning, image guided interventions, and multi-modal cancer diagnosis, staging, and therapy respo...
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Article
The influence of intraluminal thrombus on noninvasive abdominal aortic aneurysm wall distensibility measurement
Abdominal aortic aneurysm wall distensibility can be estimated by measuring pulse pressure and the corresponding sac volume change, which can be obtained by measuring wall displacement. This approach, however,...