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    Article

    Investigating the reference domain influence in personalised models of cardiac mechanics

    A major concern in personalised models of heart mechanics is the unknown zero-pressure domain, a prerequisite for accurately predicting cardiac biomechanics. As the reference configuration cannot be captured b...

    Myrianthi Hadjicharalambous in Biomechanics and Modeling in Mechanobiology (2021)

  2. Article

    Open Access

    Decompressive craniectomy of post-traumatic brain injury: an in silico modelling approach for intracranial hypertension management

    Traumatic brain injury (TBI) causes brain edema that induces increased intracranial pressure and decreased cerebral perfusion. Decompressive craniectomy has been recommended as a surgical procedure for the man...

    Chryso Lambride, Nicolas Christodoulou, Anna Michail in Scientific Reports (2020)

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    Article

    Multiscale modelling of solid tumour growth: the effect of collagen micromechanics

    Here we introduce a model of solid tumour growth coupled with a multiscale biomechanical description of the tumour microenvironment, which facilitates the explicit simulation of fibre–fibre and tumour–fibre in...

    Peter A. Wijeratne, Vasileios Vavourakis in Biomechanics and Modeling in Mechanobiology (2016)

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    Chapter and Conference Paper

    Breast Conserving Surgery Outcome Prediction: A Patient-Specific, Integrated Multi-modal Imaging and Mechano-Biological Modelling Framework

    Patient-specific surgical predictions of Breast Conserving Therapy, through mechano-biological simulations, could inform the shared decision making process between clinicians and patients by enabling the impac...

    Björn Eiben, Rene Lacher, Vasileios Vavourakis, John H. Hipwell in Breast Imaging (2016)

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    Article

    An Inverse Finite Element u/p-Formulation to Predict the Unloaded State of In Vivo Biological Soft Tissues

    Physically realistic patient-specific biomechanical modelling is of paramount importance for many medical applications, where the geometry of tissues or organs is usually constructed from in vivo images. However,...

    Vasileios Vavourakis, John H. Hipwell, David J. Hawkes in Annals of Biomedical Engineering (2016)

  6. Article

    Open Access

    Symmetric Biomechanically Guided Prone-to-Supine Breast Image Registration

    Prone-to-supine breast image registration has potential application in the fields of surgical and radiotherapy planning, image guided interventions, and multi-modal cancer diagnosis, staging, and therapy respo...

    Björn Eiben, Vasileios Vavourakis, John H. Hipwell in Annals of Biomedical Engineering (2016)

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    Article

    The influence of intraluminal thrombus on noninvasive abdominal aortic aneurysm wall distensibility measurement

    Abdominal aortic aneurysm wall distensibility can be estimated by measuring pulse pressure and the corresponding sac volume change, which can be obtained by measuring wall displacement. This approach, however,...

    Eleni Metaxa, Nikolaos Kontopodis in Medical & Biological Engineering & Computi… (2015)