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Open AccessMetabolic network alterations as a supportive biomarker in dementia with Lewy bodies with preserved dopamine transmission
Metabolic network analysis of FDG-PET utilizes an index of inter-regional correlation of resting state glucose metabolism and has been proven to provide complementary information regarding the disease process ...
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Article
Open AccessAdopting transfer learning for neuroimaging: a comparative analysis with a custom 3D convolution neural network model
In recent years, neuroimaging with deep learning (DL) algorithms have made remarkable advances in the diagnosis of neurodegenerative disorders. However, applying DL in different medical domains is usually chal...
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Open AccessA 3D deep learning model to predict the diagnosis of dementia with Lewy bodies, Alzheimer’s disease, and mild cognitive impairment using brain 18F-FDG PET
The purpose of this study is to develop and validate a 3D deep learning model that predicts the final clinical diagnosis of Alzheimer’s disease (AD), dementia with Lewy bodies (DLB), mild cognitive impairment ...
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Open AccessPhosphorylated tau181 in plasma as a potential biomarker for Alzheimer’s disease in adults with Down syndrome
Plasma tau phosphorylated at threonine 181 (p-tau181) predicts Alzheimer’s disease (AD) pathology with high accuracy in the general population. In this study, we investigated plasma p-tau181 as a biomarker of ...
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Article
Preservation of brain metabolism in recently diagnosed Parkinson’s impulse control disorders
Impulse control disorders (ICD) are a common and disrupting complication of Parkinson’s disease (PD) treatment. Although their relationship with dopaminergic activity is well studied, their brain metabolic cor...
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Article
Correction to: Superior performance of 18F-fluorocholine digital PET/CT in the detection of parathyroid adenomas
The correct administered activity of 18F-FCH is 0.1–0.14 mCi/Kg, which is equivalent to 3.7–5.2 MBq/kg.
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Article
Superior performance of 18F-fluorocholine digital PET/CT in the detection of parathyroid adenomas
To compare detectability of hyperfunctioning parathyroid tissue (HPT) by digital and analog 18F-fluorocholine PET/CT in patients with primary hyperparathyroidism and negative/inconclusive 99mTc-MIBI scintigrap...
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Article
Striking neurologic 18F-FDG PET/CT pattern in Devic’s disease (neuromyelitis optica spectrum disorder)
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Article
Digital vs. analog PET/CT: intra-subject comparison of the SUVmax in target lesions and reference regions
The purpose of this study was to assess whether digital photon counting technology in digital PET/CT influences the quantification of SUVmax in target lesions and regions of reference compared to analog PET/CT...
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Article
Comparison of image quality and lesion detection between digital and analog PET/CT
The purpose of this study was to compare image quality and lesion detection capability between a digital and an analog PET/CT system in oncological patients.
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Article
Correction to: Digital vs. analog PET/CT: intra-subject comparison of the SUVmax in target lesions and reference regions
The article Digital vs. analog PET/CT: intra-subject comparison of the SUVmax in target lesions and reference regions, written by Francisco Fuentes-Ocampo, Diego Alfonso López-Mora, Albert Flotats, Gabriela Pa...
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Article
Cortical atrophic-hypometabolic dissociation in the transition from premanifest to early-stage Huntington’s disease
Huntington’s disease (HD) is a fatal neurodegenerative disorder with no effective treatment currently available. Although the pathological hallmark of HD is massive striatal atrophy, it has been suggested that...
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Hybrid Imaging of the Head and Neck Region
The term head and neck cancer (HNC) generally encompasses malignant neoplasms of soft tissue origin of the oral cavity, lips, nasal cavity, paranasal sinuses, pharynx, larynx and salivary glands, as well as sa...
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Striking lack of visualization of striatum on 18F-FDG brain PET in chorea-acanthocytosis
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Striatal hypometabolism in premanifest and manifest Huntington’s disease patients
To assess metabolic changes in cerebral 18F-FDG PET/CT in premanifest and manifest Huntington’s disease (HD) subjects compared to a control group and to correlate 18F-FDG uptake patterns with different disease st...
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Article
Amyloid imaging in depression: a predictor of Alzheimer’s disease?
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Cardiac 123I-metaiodobenzylguanidine imaging allows early identification of dementia with Lewy bodies during life
Differential diagnosis between dementia with Lewy bodies (DLB) and other neurodegenerative diseases with cognitive impairment represents a clinical challenge. Due to the overlap** of symptoms, the clinical d...
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Visualisation of sodium-iodide symporter
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Left ventricular end-diastolic volume is decreased at maximal exercise in athletes with marked repolarisation abnormalities: a continuous radionuclide monitoring study
Although marked repolarisation abnormalities (MRAs) are considered innocuous in trained athletes, their functional significance awaits clarification. The aim of this study was to further evaluate the pathophys...
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Challenging the neuronal MIBG uptake by pharmacological intervention: effect of a single dose of oral amitriptyline on regional cardiac MIBG uptake
Imaging with metaiodobenzylguanidine (MIBG) is used for the assessment of neuronal dysfunction in various cardiovascular disorders. Although valuable information is obtained by resting MIBG imaging, it is conc...