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Article
A review of the natural history of Sturge–Weber syndrome through adulthood
Sturge–Weber syndrome (SWS) is a neurocutaneous disorder caused by a somatic mutation in the GNAQ gene, leading to capillary venous malformations with neurological, ocular, and cutaneous abnormalities. Descriptio...
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Article
Epilepsy related to focal neuronal lipofuscinosis: extra-frontal localization, EEG signatures and GABA involvement
Focal neuronal lipofuscinosis (FNL) is an uncommon epileptic disorder related to an excess of lipofuscin accumulation within dysmorphic-appearing neurons (DANs), whose epileptogenic mechanisms are still poorly...
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Article
Neuron Specific Enolase, S100-beta protein and progranulin as diagnostic biomarkers of status epilepticus
Status epilepticus (SE) is a life-threatening prolonged epileptic seizure. A rapid diagnosis is fundamental to initiate antiepileptic treatment and to prevent the development of neurological sequels. Several s...
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Article
Open AccessA self-supervised learning strategy for postoperative brain cavity segmentation simulating resections
Accurate segmentation of brain resection cavities (RCs) aids in postoperative analysis and determining follow-up treatment. Convolutional neural networks (CNNs) are the state-of-the-art image segmentation tech...
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Article
An Uncommon Case of Hyperammonemic Encephalopathy
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Article
Open AccessThe pharmacological perturbation of brain zinc impairs BDNF-related signaling and the cognitive performances of young mice
Zinc (Zn2+) is a pleiotropic modulator of the neuronal and brain activity. The disruption of intraneuronal Zn2+ levels triggers neurotoxic processes and affects neuronal functioning. In this study, we investigate...
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Article
Open AccessMild Acidosis Enhances AMPA Receptor-Mediated Intracellular Zinc Mobilization in Cortical Neurons
Overactivation of glutamate receptors and subsequent deregulation of the intraneuronal calcium ([Ca2+]i) levels are critical components of the injurious pathways initiated by cerebral ischemia. Another hallmark o...
