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Article
Open AccessCorrection: Utility of copeptin in predicting non-pathological postoperative polyuria in patients affected by acromegaly undergoing pituitary neurosurgery
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Article
Open AccessUtility of copeptin in predicting non-pathological postoperative polyuria in patients affected by acromegaly undergoing pituitary neurosurgery
Copeptin efficiently predicts post-neurosurgical central diabetes insipidus (CDI) in patients with hypothalamic-pituitary lesions, but its role in characterizing changes in diuresis in individuals with acromeg...
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Article
Iperplasia ipofisaria da ipotiroidismo primitivo cronicamente scompensato
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Article
Open AccessProlactin-secreting tumors, dopamine agonists and pregnancy: a longitudinal experience of a tertiary neuroendocrine center
Prolactin (PRL)-secreting tumours are associated with infertility and can be reverted by dopamine agonist (DA) therapy. The suspension of DA is recommended once pregnancy is established, as all DAs cross the p...
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Article
Open AccessAre prolactin levels efficient in predicting a pituitary lesion in patients with hyperprolactinemia?
Data regarding the presence of a prolactin (PRL) threshold above which a pituitary magnetic resonance imaging (MRI) is mandatory in patients with hyperprolactinemia (hyperPRL) are controversial and derived pri...
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Article
Open AccessTest diagnostici per il diabete insipido: un aggiornamento
Il corretto riconoscimento dei casi di diabete insipido, in particolar modo parziale, rimane tutt’oggi una sfida per l’endocrinologo. Nuovi test di stimolo, osmotici e non, che prevedono la determinazione plas...
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Article
Open AccessStrumenti per la lettura critica di metanalisi e revisioni sistematiche: il punto di vista del clinico
La metanalisi è una tecnica statistica con cui è possibile combinare quantitativamente i risultati di multipli studi scientifici che valutano un medesimo outcome. Una lettura consapevole di uno studio metanali...
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Article
Terapie ormonali sostitutive nella gestante ipopituitarica
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Article
Gestione diagnostica dell’incidentaloma ipofisario
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Article
HLA DRB1*0415: a new possible genetic susceptibility factor for Hirata’s disease
Hirata’s disease (HD) is a rare autoimmune cause of hypoglycemia. Patients suffering from this condition have a genetic predisposition, determined by HLA DR4, with some differences in the worldwide population....
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Article
Progression of pituitary tumours: impact of GH secretory status and long-term GH replacement therapy
Most patients treated for hypothalamic–pituitary tumours develop GH deficiency. Long-term GH replacement treatment in adults with a previous history of hypothalamic–pituitary tumour could represent a concern a...
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Living Reference Work Entry In depth
Physiopathology, Diagnosis, and Treatment of Hyperprolactinemia
Prolactin is a pituitary hormone that plays a pivotal role in a variety of reproductive functions. Hyperprolactinemia is a common condition that can result from a number of causes, including medication use and...
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Reference Work Entry In depth
Physiopathology, Diagnosis, and Treatment of Hyperprolactinemia
Prolactin is a pituitary hormone that plays a pivotal role in a variety of reproductive functions. Hyperprolactinemia is a common condition that can result from a number of causes, including medication use and...
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Article
Acylated ghrelin as provocative test for the diagnosis of ACTH deficiency in patients with hypothalamus–pituitary disease
The insulin tolerance test (ITT) is the gold standard to evaluate adrenocorticotropic hormone (ACTH) insufficiency. However, alternative tests have been proposed such as metyrapone, glucagon, and ACTH stimula...
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Article
Association of craniopharyngioma and pituitary adenoma
Intracranial tumors of different histologic types infrequently affect patients with pituitary adenomas and no history of head irradiation. The association with craniopharyngioma is extremely rare. Aims of this...
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Article
Ruolo del surrene nelle varie fasi dello sviluppo puberale
La steroidogenesi surrenalica, essenziale per la sopravvivenza e la riproduzione, inizia in età fetale ma rimane quiescente sino ai 6–7 anni quando, con l’esordio dell’adrenarca, inizia a maturare la zona reti...
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Article
L’ipopituitarismo post trauma cranico: dall’età pediatrica all’età adulta
L’ipopituitarismo post trauma cranico nel soggetto adulto è un evento di frequente riscontro e le disfunzioni ormonali conseguenti al trauma possono contribuire ad una ripresa funzionale meno rapida o non comp...
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Article
Hypopituitarism following brain injury: when does it occur and how best to test?
Aim of this review is to highlight how and when Traumatic Brain Injury (TBI) as well as Subarachnoid Haemorrhage (SAH) and primary Brain Tumours (pBT) of the Central Nervous System (CNS) can induce hypopituita...
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Article
Sindrome della sella vuota
Si definisce “sella vuota” l’erniazione dello spazio subaracnoideo all’interno del cavo sellare con conseguente appiattimento del parenchima ipofisario, che risulta così addossato al pavimento sellare. La sell...
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Chapter
Ghrelin in the Regulation of GH Secretion and Other Pituitary Hormones
Ghrelin, a 28 amino acid octanoylated peptide predominantly produced by the stomach, was discovered to be the natural ligand of the type 1a growth hormone (GH) secretagogue receptor (GHS-R1a). Thus, it was con...
