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Article
Exposition of Phosphatidylserine in Lewis Carcinoma Cells under the Action of Anphen Sodium and Hydrogen Peroxide
The apoptotic effect of the antioxidant anphen sodium, a spatially hindered phenol, which has antitumor activity—in particular, inhibiting the development of tumor cells in sarcoma—has been studied. It was fou...
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Article
The Antineoplastic Properties and Mechanism of Interaction of an Antioxidant, Sodium 2-Carboxy-2-(N-Aсetylamino)-3-(3,5-di-tert-Butyl-4-Hydroxyphenyl)Propionate, with Peptides in an Aqueous Environment According to the Data of the Calculation by Quantum Chemistry Methods
The antineoplastic properties of an antioxidant, sodium 2-carboxy-2-(N-acetylamino)-3-(3,5-di-tert-butyl-4-hydroxyphenyl)propionate, are studied on an ascites tumor, Sarcoma 37, and on a solid tumor, Lewis carcin...
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Article
Apoptotic effect of the anphen sodium antioxidant in combination with H2O2 on Lewis carcinoma cells
It was shown by immunoblotting that the introduction of an antitumor antioxidant, sodium 2-carboxy-2-(N-acetylamino)-3-(3,5-di-tert-butyl-4-hydrophenyl)propanoate (anphen sodium), into a suspension of Lewis carci...
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Article
Effect of Promising Antitumor Phenolic Antioxidant Anphen Sodium on the BCL-2 Family Proteins
The proapoptotic effect of anphen (the effect on the level of the antiapoptotic protein Bcl-2) was investigated by immunoblotting. Incubation of Lewis carcinoma cell suspension with anphen at a concentration o...
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Article
Decrease in Bcl-2 Protein Level during the Development of Lewis Carcinosarcome
We studied the development of Lewis carcinoma and possible antitumor effect of preliminary administered antioxidant anphen. The tumor was intramuscularly transplanted to C57Bl×DBA mice (7×106 cells per mouse). Ac...
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Article
Effect of oregano essential oil on the engraftment and development of Lewis carcinoma in F1 DBA C57 black hybrid mice
The effect of a low uptake dose of oregano essential oil with drinking water for three months (Origanum vulgare L.) on the degree of Lewis carcinoma engraftment and some parameters of oxidative stress has been st...
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Article
Structure and biological properties of sodium and potassium 1-(carboxy)-1-(N-methylamide)-2-(3′,5′-di-tert-butyl)-4-hydroxyphenyl)-propionates
Sodium (1) and potassium (2) 1-(carboxy)-1-(N-methylamide)-2-(3′,5′-di-tert-butyl)-4-hydroxyphenyl)-propionates form crystal hydrates, which exist as both monomers and dimers. Quantum-chemical calculations in the...
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Article
The effect of volatile antioxidants of plant origin on leukemogenesis in mice
The effect of savory essential oil added with drinking water (150 ng/ml) or with feed (2.5 μg/g) on the lifetime of AKR mice and the parameters of oxidative stress in animal blood were investigated. It was fou...
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Article
Study of the effect of melafen at low doses on animal malignant neoplasms in vivo and in vitro
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Article
Effect of antioxidant β-(4-hydroxy-3,5-ditertbutylphenyl)Propionic acid (phenosan) on the development of malignant neoplasms
The effect of different doses of synthetic antioxidant β-(4-hydroxy-3,5-ditertbutylphenyl)propionic acid (phenosan) on the development of spontaneous leukemia in AKR mice was studied. The drug efficiency was d...
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Chapter and Conference Paper
Speckle Interferometry with the BTA Telescope
The description of a speckle camera used with the BTA 6-meter telescope is given. Observational data recorded on photographic film are processed with a Fourier optical spectrum analyzer. Results of binary star...