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Article
Fine particulate matter and sleep-disordered breathing severity in a large Italian cohort
Air pollution and obstructive sleep apnea (OSA) are both linked with cardiovascular co-morbidities and share similar pathophysiological mechanisms. A causal association between the two has been postulated. How...
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Article
Recombinant human chorionic gonadotropin and gonadotropin-releasing hormone agonist differently affect the profile of extracellular vesicle microRNAs in human follicular fluid
To compare the expression profile of extracellular vesicle microRNAs (EV-miRNAs) derived from follicular fluid after a trigger with recombinant human chorionic gonadotropin (r-hCG) or with a gonadotropin-relea...
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Article
Open AccessDepression and cardiovascular risk—association among Beck Depression Inventory, PCSK9 levels and insulin resistance
Depression and cardiovascular disease (CVD) are among the most common causes of disability in high-income countries, depression being associated with a 30% increased risk of future CV events. Depression is twi...
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Article
Open AccessParticulate matter exposure shapes DNA methylation through the lifespan
Exposure to airborne particulate matter (PM) has been associated with detrimental health effects. DNA methylation represents the most well-studied epigenetic factor among the possible mechanisms underlying thi...
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Article
Open AccessUrinary chromium is associated with changes in leukocyte miRNA expression in obese subjects
Epidemiological studies suggest a link between chromium (Cr) status and cardiovascular disease. Increased urinary excretion of Cr was reported in subjects with diabetes compared with non-diabetic controls and ...
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Article
Open AccessRepetitive element hypermethylation in multiple sclerosis patients
Multiple sclerosis (MS) is a complex disorder of the central nervous system whose cause is currently unknown. Evidence is increasing that DNA methylation alterations could be involved in inflammatory and neuro...
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Article
Environmental epigenetics
Epigenetics investigates heritable changes in gene expression that occur without changes in DNA sequence. Several epigenetic mechanisms, including DNA methylation and histone modifications, can change genome f...
