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    Mechanisms of Toxic Effect of Streptozotocin on β-Cells in the Islets of Langerhans

    Administration of streptozotocin caused selective damage to endocrine β-cells in rat pancreatic islets, which was related to activation of apoptosis. The cytotoxic effect of streptozotocin was associated not o...

    V. B. Pisarev, G. L. Snigur, A. A. Spasov in Bulletin of Experimental Biology and Medic… (2009)

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    Ultrastructure of neurons in the hypothalamic suprachiasmatic nucleus of rats with different stress reactivity

    The rats were divided into groups demonstrating extremely high and low stress reactivity depending on the results of testing for the nociceptive threshold and thermolability in response to bacterial lipopolysa...

    M. B. Potanin, V. P. Tumanov in Bulletin of Experimental Biology and Medicine (2007)

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    Variability of neuronal damage and proportion of activities of NO synthase isoforms during cerebral ischemia/reperfusion in rats

    We studied expression of endothelial and neuronal NO synthase isoforms and severity of ischemia/reperfusion-induced damage to neurons in different brain compartments in albino rats. The peculiarities of distri...

    V. I. Petrov, V. B. Pisarev, E. A. Ponomarev in Bulletin of Experimental Biology and Medic… (2007)

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    Ultrastructural changes in the lateral reticular nucleus of the medulla oblongata in prepubertal rats under the effect of long-term stress exposure

    Ultrastructural changes in the lateral reticular nuclei of the medulla oblongata of rat pups develo** under the effect of chronic mental and pain stress indicate impaired histogenesis of structures of the me...

    A. V. Smirnov, V. B. Pisarev in Bulletin of Experimental Biology and Medic… (2007)

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    Effects of L-, D-, and DL-carnitine on morphometric parameters of skeletal muscle and exercise performance of laboratory animals receiving carnitine-deficient diet

    Serum concentration of L-carnitine, the mean thickness of the skeletal muscle fiber, and exercise performance in the forced swimming test decreased in rats receiving a carnitine-deficient diet. Treatment with ...

    A. A. Spasov, I. N. Iezhitsa in Bulletin of Experimental Biology and Medic… (2006)

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    Structural Changes in the Nucleus Ambiguus of the Medulla Oblongata and Intracardiac Ganglia in Growing Rats in Immobilization Stress

    The aim of the present work was to study qualitative and quantitative measures of histological changes in the nucleus ambiguus (NA) of the medulla oblongata and the cardiac autonomic ganglia (CAG) in growing a...

    A. V. Smirnov, V. B. Pisarev, R. P. Samusev in Neuroscience and Behavioral Physiology (2006)

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    Ultrastructural Changes in Neurons of Medullary Giant-Cell Nucleus in Growing Rat Exposed to Acute Stress

    Ultrastructural transformations in neurons of the medullary giant-cell reticular nucleus of young rats during exposure to acute emotional and painful stress attest to activation of the protein synthesis system...

    V. B. Pisarev, A. V. Smirnov in Bulletin of Experimental Biology and Medic… (2005)

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    Morphofunctional Characteristics of Antigen-Presenting Cells in Lymph Node in Mice with Experimental West Nile Fever

    Pronounced transformation of cells in mesenteric lymph nodes, mainly in the thymus-independent zone and sinuses, was detected in albino mice experimentally infected with West Nile fever (strain 986). Maximum a...

    V. B. Pisarev, E. O. Shishkina in Bulletin of Experimental Biology and Medic… (2003)

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    The use of porous polysulfone as a new material for intraorbital implantation

    Porous polysulfone is tested in animals for use as an implant during the formation of the postenucleation stump. It is shown that such an implant not only becomes encapsulated as a foreign body but also forms ...

    V. B. Pisarev, Kh. Kh. Mukhaev in Bulletin of Experimental Biology and Medicine (1996)

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    The role of various hierarchic structures of the brain in psychoemotional stress

    The hypothalamus is the brain structure the most involved in the formation of the stress reaction.

    V. B. Pisarev, V. P. Tumanov, A. Yu. Erofeev in Bulletin of Experimental Biology and Medic… (1996)

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    Modular organization of the rat hypothalamus

    V. B. Pisarev, V. P. Tumanov in Bulletin of Experimental Biology and Medicine (1992)

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    Mechanism of formation of the integral hypothalamic response during psychoemotional overstrain

    V. P. Tumanov, V. B. Pisarev in Bulletin of Experimental Biology and Medicine (1991)