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Open AccessIRF4 and BATF are critical for CD8+ T-cell function following infection with LCMV
CD8+ T-cell functions are critical for preventing chronic viral infections by eliminating infected cells. For healthy immune responses, beneficial destruction of infected cells must be balanced against immunopath...
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Article
Open AccessReactive oxygen species delay control of lymphocytic choriomeningitis virus
Cluster of differentiation (CD)8+ T cells are like a double edged sword during chronic viral infections because they not only promote virus elimination but also induce virus-mediated immunopathology. Elevated lev...