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Article
Open AccessDistinct role of histone chaperone Asf1a and Asf1b during fertilization and pre-implantation embryonic development in mice
Asf1 is a well-conserved histone chaperone that regulates multiple cellular processes in different species. Two paralogous genes, Asf1a and Asf1b exist in mammals, but their role during fertilization and early...
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Article
Open AccessThe extent of liver injury determines hepatocyte fate toward senescence or cancer
It is well known that induction of hepatocyte senescence could inhibit the development of hepatocellular carcinoma (HCC). Until now, it is still unclear how the degree of liver injury dictates hepatocyte senes...
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Article
Open AccessmicroRNA-501-3p suppresses metastasis and progression of hepatocellular carcinoma through targeting LIN7A
Increasing numbers of evidences have demonstrated that microRNAs (miRNAs) are implicated in metastasis and progression of hepatocellular carcinoma (HCC). However, their detailed expression levels and actual fu...
