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  1. Article

    Open Access

    Identification of the allosteric P2X7 receptor antagonist [11C]SMW139 as a PET tracer of microglial activation

    The P2X7 receptor plays a significant role in microglial activation, and as a potential drug target, the P2X7 receptor is also an interesting target in positron emission tomography. The current study aimed at the...

    Bieneke Janssen, Danielle J. Vugts, Shane M. Wilkinson, Dieter Ory… in Scientific Reports (2018)

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  2. Article

    Open Access

    18th European Symposium on Radiopharmacy and Radiopharmaceuticals

    OP03 Selective extraction of medically-related radionuclides from proton-irradiated thorium targets

    V. Radchenko, J. W. Engle, C. Roy, J. Griswold… in EJNMMI Radiopharmacy and Chemistry (2016)

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  3. No Access

    Chapter

    Imaging Histamine Receptors Using PET and SPECT

    The histaminergic system contains four subtypes of G-protein-coupled receptors: H1R, H2R, H3R and H4R. In the central nervous system, they mediate the action of histamine in pituitary hormone secretion, wakefulne...

    Uta Funke, Danielle J. Vugts, Bieneke Janssen… in PET and SPECT of Neurobiological Systems (2014)

  4. No Access

    Article

    Assessment of α7 nicotinic acetylcholine receptor availability in juvenile pig brain with [18F]NS10743

    To conduct a quantitative PET assessment of the specific binding sites in the brain of juvenile pigs for [18F]NS10743, a novel diazabicyclononane derivative targeting α7 nicotinic acetylcholine receptors (α7 nACh...

    Winnie Deuther-Conrad, Steffen Fischer… in European Journal of Nuclear Medicine and M… (2011)