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Article
Urine tricarboxylic acid cycle signatures of early-stage diabetic kidney disease
Urine tricarboxylic acid (TCA) cycle organic anions (OAs) are elevated in diabetes and may be biomarkers for diabetic kidney disease (DKD) progression.
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Article
Open AccessUrinalysis findings and urinary kidney injury biomarker concentrations
Urinary biomarkers of kidney injury are presumed to reflect renal tubular damage. However, their concentrations may be influenced by other factors, such as hematuria or pyuria. We sought to examine what non-in...
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Article
Open AccessTraditional medicine practices among community members with diabetes mellitus in Northern Tanzania: an ethnomedical survey
Diabetes is a growing burden in sub-Saharan Africa where traditional medicines (TMs) remain a primary form of healthcare in many settings. In Tanzania, TMs are frequently used to treat non-communicable disease...
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Article
Open AccessJoint Effect of Early Microvascular Damage in the Eye & Kidney on Risk of Cardiovascular Events
Microalbuminuria is associated with an increased risk of cardiovascular disease (CVD), but not all individuals require treatment. Retinal microvascular abnormalities and microalbuminuria reflect early systemic...
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Article
Open AccessNeighborhood clustering of non-communicable diseases: results from a community-based study in Northern Tanzania
In order to begin to address the burden of non-communicable diseases (NCDs) in sub-Saharan Africa, high quality community-based epidemiological studies from the region are urgently needed. Cluster-designed sam...
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Article
Open AccessPrevalence and correlates of proteinuria in Kampala, Uganda: a cross-sectional pilot study
Despite the increasing prevalence of chronic kidney disease (CKD) in sub-Saharan Africa, few community-based screenings have been conducted in Uganda. Opportunities to improve the management of CKD in sub-Saha...
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Article
Open AccessTraditional medicine practices among community members with chronic kidney disease in northern Tanzania: an ethnomedical survey
In sub-Saharan Africa, chronic kidney disease (CKD) is being recognized as a non-communicable disease (NCD) with high morbidity and mortality. In countries like Tanzania, people access many sources, including ...
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Article
The quality of cardiovascular disease care for adolescents with kidney disease: a Midwest Pediatric Nephrology Consortium study
Cardiovascular disease is the leading cause of increased mortality for adolescents with advanced kidney disease. The quality of preventive cardiovascular care may impact long-term outcomes for these patients.
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Article
Open AccessComparison of outcomes for veterans receiving dialysis care from VA and non-VA providers
Demand for dialysis treatment exceeds its supply within the Veterans Health Administration (VA), requiring VA to outsource dialysis care by purchasing private sector dialysis for veterans on a fee-for-service ...
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Article
Open AccessImplementation of automated reporting of estimated glomerular filtration rate among Veterans Affairs laboratories: a retrospective study
Automated reporting of estimated glomerular filtration rate (eGFR) is a recent advance in laboratory information technology (IT) that generates a measure of kidney function with chemistry laboratory results to...
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Article
Open AccessAssociation between high-dose erythropoiesis-stimulating agents, inflammatory biomarkers, and soluble erythropoietin receptors
High-dose erythropoiesis-stimulating agents (ESA) for anemia of chronic kidney disease (CKD) have been associated with adverse clinical outcomes and do not always improve erythropoiesis. We hypothesized that h...
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Article
Open AccessThe Chronic Kidney Disease Model: A General Purpose Model of Disease Progression and Treatment
Chronic kidney disease (CKD) is the focus of recent national policy efforts; however, decision makers must account for multiple therapeutic options, comorbidities and complications. The objective of the Chroni...
