3 Result(s)
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Una O’Doherty
Protein Structure
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Article
Open AccessMeasuring integrated HIV DNA ex vivo and in vitro provides insights about how reservoirs are formed and maintained
The identification of the most appropriate marker to measure reservoir size has been a great challenge for the HIV field. Quantitative viral outgrowth assay (QVOA), the reference standard to quantify the amoun...
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Article
Open AccessBeyond the replication-competent HIV reservoir: transcription and translation-competent reservoirs
Recent years have seen a substantial increase in the number of tools available to monitor and study HIV reservoirs. Here, we discuss recent technological advances that enable an understanding of reservoir dyna...
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Article
Open AccessHIV latency and integration site placement in five cell-based models
HIV infection can be treated effectively with antiretroviral agents, but the persistence of a latent reservoir of integrated proviruses prevents eradication of HIV from infected individuals. The chromosomal en...
