12 Result(s)
within
Tsuyoshi Miyazaki
Rheumatology
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Article
Open AccessNon-inferior comparative study comparing one or two day antimicrobial prophylaxis after clean orthopaedic surgery (NOCOTA study): a study protocol for a cluster pseudo-randomized controlled trial comparing duration of antibiotic prophylaxis
Antimicrobial prophylaxis (AMP) is one of the most important measures for preventing surgical site infections (SSIs); however, controversies remain regarding its adequate duration. Although the World Health Or...
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Article
Open AccessIntraarticular injection of processed lipoaspirate cells has anti-inflammatory and analgesic effects but does not improve degenerative changes in murine monoiodoacetate-induced osteoarthritis
Previous basic research and clinical studies examined the effects of mesenchymal stem cells (MSCs) on regeneration and maintenance of articular cartilage. However, our pilot study suggested that MSCs are more ...
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Article
Two novel sandwich ELISAs identify PAD4 levels and PAD4 autoantibodies in patients with rheumatoid arthritis
The peptidylarginine deiminase 4 (PAD4) gene and PAD4 autoantibodies have been associated with rheumatoid arthritis (RA) and its pathogenesis. Therefore, methods for accurately determining their levels in the ...
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Article
Anteroposterior and varus–valgus laxity of the knee increase after stair climbing in patients with mild osteoarthritis
The aim of this study was to measure exercise-induced changes in knee joint laxity in patients with knee osteoarthritis (OA). The study subjects were 46 female patients with OA and 22 age- and sex-matched norm...
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Article
Open AccessMaintenance of mitochondrial DNA copy number is essential for osteoclast survival
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Article
Open AccessDirect transplantation of mesenchymal stem cells into the knee joints of Hartley strain guinea pigs with spontaneous osteoarthritis
Mesenchymal stem cells (MSCs) can differentiate into various connective tissue cells. Several techniques have been used for the clinical application of MSCs in articular cartilage repair; however, there are ma...
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Article
Neutrophil CD64 expression as a diagnostic marker for local infection and crystal-induced arthritis
The usefulness of neutrophil CD64 expression was examined in diagnosing local infection, including soft tissue, bone, and joint infections. Among 99 patients suspected of local infection, 31 were confirmed and...
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Article
Rheumatoid arthritis associated with osteopetrosis
Osteopetrosis is an inherited disorder characterized by reduced bone resorption. We here report a rare case of osteopetrosis associated with rheumatoid arthritis. The patient was diagnosed as autosomal dominan...
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Article
Direct detection of pathogens in osteoarticular infections by polymerase chain reaction amplification and microarray hybridization
Molecular biological techniques such as the polymerase chain reaction (PCR) and DNA microarray are used for the detection/identification of microorganisms; however, few reports have discussed the clinical util...
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Article
Exceedingly large femoral condyle intraosseous ganglion cyst following high tibial osteotomy
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Article
Subcutaneous tendon rupture of extensor tendons on bilateral wrists associated with calcium pyrophosphate dihydrate crystal deposition disease
Calcium pyrophosphate dihydrate (CPPD) crystal deposition disease is a well-recognized inflammatory joint disorder. Extensor tendon rupture associated with CPPD deposition has rarely been described. We report ...
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Article
The role of c-Src kinase in the regulation of osteoclast function
The targeted disruption of c-Src impairs osteoclast bone resorbing activity, causing osteopetrosis. Although it has been reported that restoring only the c-Src adaptor function at least partly rescues the skel...
