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  1. Article

    Open Access

    Gradual loaded exercise of knee extension muscles using an orthosis after wide resection of a femoral sarcoma and quadriceps muscle: a case report

    Details of improved gait ability after wide resection of soft tissue sarcomas that necessitate removal of portions of the quadricep muscle have not yet been reported. We describe a patient with improved gait a...

    Ippei Kitade, Hisashi Oki, Takumi Sakamoto in Journal of Medical Case Reports (2023)

  2. Article

    Open Access

    Lung adenocarcinoma and squamous cell carcinoma difficult for immunohistochemical diagnosis can be distinguished by lipid profile

    In patients with unresectable non-small cell lung cancer, histological diagnosis is frequently based on small biopsy specimens unsuitable for histological diagnosis when they are severely crushed and do not re...

    Takashi Yamashita, Yusuke Takanashi, Asuka Uebayashi, Mikako Oka in Scientific Reports (2023)

  3. Article

    Open Access

    Coenzyme Q10 in the eye isomerizes by sunlight irradiation

    Photoisomerization of lipids has been well studied. As for the eyes, photoisomerization from 11-cis isomer to all-trans-retinal is well-known as the first step of the visual transduction in the photoreceptors. In...

    Md. Al Mamun, Md. Mahamodun Nabi, Tomohito Sato, Shuhei Aramaki in Scientific Reports (2022)

  4. Article

    Open Access

    Intraarticular injection of processed lipoaspirate cells has anti-inflammatory and analgesic effects but does not improve degenerative changes in murine monoiodoacetate-induced osteoarthritis

    Previous basic research and clinical studies examined the effects of mesenchymal stem cells (MSCs) on regeneration and maintenance of articular cartilage. However, our pilot study suggested that MSCs are more ...

    Takumi Sakamoto, Tsuyoshi Miyazaki, Shuji Watanabe in BMC Musculoskeletal Disorders (2019)

  5. Article

    Open Access

    CD271-selected mesenchymal stem cells from adipose tissue enhance cartilage repair and are less angiogenic than plastic adherent mesenchymal stem cells

    CD271 is a marker of bone marrow MSCs with enhanced differentiation capacity for bone or cartilage repair. However, the nature of CD271+ MSCs from adipose tissue (AT) is less well understood. Here, we investig...

    Nupur Kohli, Ibtesam R. T. Al-Delfi, Martyn Snow, Takumi Sakamoto in Scientific Reports (2019)

  6. No Access

    Chapter

    Targeted Retrograde Gene Delivery into the Injured Spinal Cord Using Recombinant Adenovirus Vector Carrying Neurotrophic Factor Gene

    We investigated the efficacy of retrograde gene delivery via the sternomastoid muscle of recombinant adenovirus vector (AdV) carrying brain-derived neurotrophic factor (BDNF) gene for the rescue of injured rat...

    Hideaki Nakajima, Kenzo Uchida in Neuroprotection and Regeneration of the Sp… (2014)