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Metabolic bone disorders after gastrectomy: inevitable or preventable?

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  1. Article

    Open Access

    The clinical impacts of postoperative complications after colon cancer surgery for the clinical course of adjuvant treatment and survival

    We investigated whether or not postoperative complications (POCs) themselves have a negative survival impact or indirectly worsen the survival due to insufficient adjuvant chemotherapy in a pooled analysis of ...

    Toru Aoyama, Koji Oba, Michitaka Honda in International Journal of Clinical Oncology (2023)

  2. Article

    Open Access

    Clinical practice guidelines for duodenal cancer 2021

    Duodenal cancer is considered to be a small intestinal carcinoma in terms of clinicopathology. In Japan, there are no established treatment guidelines based on sufficient scientific evidence; therefore, in dai...

    Kenji Nakagawa, Masayuki Sho, Mitsuhiro Fujishiro in Journal of Gastroenterology (2022)

  3. Article

    Open Access

    Does the Endoscopic Surgical Skill Qualification System improve patients’ outcome following laparoscopic surgery for colon cancer? A multicentre, retrospective analysis with propensity score matching

    This study aimed to investigate the short-term and oncological impact of the Endoscopic Surgical Skill Qualification System (ESSQS) by the Japan Society for Endoscopic Surgery on the operator performing laparo...

    Keisuke Kazama, Masakatsu Numata, Toru Aoyama in World Journal of Surgical Oncology (2021)

  4. Article

    Equivalent feasibility and safety of perioperative care by ERAS in open and laparoscopy-assisted distal gastrectomy for gastric cancer: a single-institution ancillary study using the patient cohort enrolled in the JCOG0912 phase III trial

    Laparoscopy-assisted distal gastrectomy (LADG) has an advantage of earlier recovery after surgery due to having lower invasiveness and wound pain than open distal gastrectomy (ODG). However, whether the same e...

    Toru Aoyama, Takaki Yoshikawa, Tsutomu Sato, Tsutomu Hayashi in Gastric Cancer (2019)

  5. Article

    Changes in bone metabolism after gastric cancer surgery in male patients: a prospective observational study

    Several retrospective studies have shown that bone disorders occur after gastric cancer surgery. This study was designed to prospectively evaluate the changes in bone metabolism after gastrectomy for gastric c...

    Yosuke Atsumi, Yasushi Rino, Hiroo Wada, Yuichi Kitani, Yukihiro Ozawa in Gastric Cancer (2019)

  6. Article

    A phase II trial of capecitabine plus cisplatin (XP) for patients with advanced gastric cancer with early relapse after S-1 adjuvant therapy: XParTS-I trial

    In Japan, standard regimens for advanced gastric cancer (AGC) include S-1 chemotherapy. The standard treatment for early relapse after adjuvant chemotherapy with fluoropyrimidine alone is platinum-based chemot...

    Kazuhiro Nishikawa, Akira Tsuburaya, Takaki Yoshikawa, Masazumi Takahashi in Gastric Cancer (2018)

  7. Article

    Priority of lymph node dissection for proximal gastric cancer invading the greater curvature

    The therapeutic efficacy of dissection of the splenic hilar lymph nodes (#10) has not been fully evaluated in locally advanced proximal gastric cancer (LAGC) invading the greater curvature of the stomach.

    Yukio Maezawa, Toru Aoyama, Takanobu Yamada, Kazuki Kano, Tsutomu Hayashi in Gastric Cancer (2018)

  8. Article

    Does a laparoscopic approach attenuate the body weight loss and lean body mass loss observed in open distal gastrectomy for gastric cancer? a single-institution exploratory analysis of the JCOG 0912 phase III trial

    Laparoscopy-assisted distal gastrectomy (LADG) for gastric cancer may prevent the loss of body weight and lean body mass resulting from reduced surgical stress in comparison to open distal gastrectomy (ODG). A...

    Toru Aoyama, Tsutomu Sato, Tsutomu Hayashi, Takanobu Yamada, Haruhiko Cho in Gastric Cancer (2018)

  9. Article

    Open Access

    Prediction of postoperative inflammatory complications after esophageal cancer surgery based on early changes in the C-reactive protein level in patients who received perioperative steroid therapy and enhanced recovery after surgery care: a retrospective analysis

    Serum C-reactive protein (CRP) level can be an indicator of the early stage of infectious complications. However, its utility in advanced esophageal cancer patients who receive radical esophagectomy with two- ...

    Kazuki Kano, Toru Aoyama, Tetsushi Nakajima, Yukio Maezawa, Tsutomu Hayashi in BMC Cancer (2017)

  10. Article

    Impact of preoperative hand grip strength on morbidity following gastric cancer surgery

    Sarcopenia is a decrease in both muscle mass and strength. It remains unclear whether sarcopenia is associated with morbidity after gastric cancer surgery. This study evaluated the impact of sarcopenia on the ...

    Tsutomu Sato, Toru Aoyama, Tsutomu Hayashi, Kenki Segami, Taiichi Kawabe in Gastric Cancer (2016)

  11. Article

    Quality of life and nutritional consequences after aboral pouch reconstruction following total gastrectomy for gastric cancer: randomized controlled trial CCG1101

    Total gastrectomy has detrimental effects on postoperative nutritional status and quality of life (QOL), but it is often unavoidable in the treatment of gastric cancer. Roux-en-Y (RY) is the most common recon...

    Yuichi Ito, Takaki Yoshikawa, Michitaka Fujiwara, Hiroshi Kojima in Gastric Cancer (2016)

  12. Article

    Body composition analysis within 1 month after gastrectomy for gastric cancer

    A significant body weight loss (BWL) is observed during 1 month after gastrectomy for gastric cancer. However, it remains unclear which body component mainly accounts for the weight loss.

    Toru Aoyama, Taiichi Kawabe, Fujikawa Hirohito, Tsutomu Hayashi in Gastric Cancer (2016)

  13. Article

    The survival difference between gastric cancer patients from the UK and Japan remains after weighted propensity score analysis considering all background factors

    Previous studies comparing survival between gastric cancer (GC) patients from the West and the East were based on the assumption that background factors and prognostic factors were identical. The aim of the cu...

    Takanobu Yamada, Takaki Yoshikawa, Masataka Taguri, Tsutomu Hayashi in Gastric Cancer (2016)

  14. Article

    Impact of infectious complications on gastric cancer recurrence

    Postoperative infectious complications increase disease recurrence in colorectal cancer patients. We herein investigated the impact of infectious complications on gastric cancer recurrence after curative surgery.

    Tsutomu Hayashi, Takaki Yoshikawa, Toru Aoyama, Shinichi Hasegawa in Gastric Cancer (2015)

  15. Article

    Open Access

    Methylene blue-assisted technique for harvesting lymph nodes after radical surgery for gastric cancer: a prospective randomized phase III study

    This randomized Phase III trial will evaluate whether the methylene blue-assisted technique is efficient for harvesting lymph nodes after radical surgery for gastric cancer.

    Toru Aoyama, Takaki Yoshikawa, Satoshi Morita, Junya Shirai in BMC Cancer (2014)

  16. Article

    Laparoscopic esophagojejunostomy using the EndoStitch and a circular stapler under a direct view created by the ENDOCAMELEON

    Laparoscopic esophagojejunostomy using a circular stapler is associated with technical difficulties in the purse-string sutures used to insert the anvil head and in obtaining an adequate visual field to preven...

    Takaki Yoshikawa, Tsutomu Hayashi, Toru Aoyama, Haruhiko Cho in Gastric Cancer (2013)

  17. Article

    A prospective feasibility and safety study of laparoscopy-assisted distal gastrectomy for clinical stage I gastric cancer initiated by surgeons with much experience of open gastrectomy and laparoscopic surgery

    The aim of this prospective study was to evaluate the feasibility and safety of laparoscopy-assisted distal gastrectomy (LADG) initiated by surgeons with much experience of open gastrectomy and laparoscopic su...

    Takaki Yoshikawa, Haruhiko Cho, Yasushi Rino, Yuji Yamamoto in Gastric Cancer (2013)

  18. Article

    Risk factors for 6-month continuation of S-1 adjuvant chemotherapy for gastric cancer

    The factors that affect the 6-month continuation of adjuvant chemotherapy with S-1 have not been fully evaluated. The objective of this retrospective study was to clarify the risk factors for 6-month continuat...

    Toru Aoyama, Takaki Yoshikawa, Tsutomu Hayashi, Hiroshi Kuwabara in Gastric Cancer (2013)

  19. Article

    Safety and feasibility of S-1 adjuvant chemotherapy for gastric cancer in elderly patients

    The safety and feasibility of administering S-1 adjuvant chemotherapy for gastric cancer has not been fully evaluated in elderly patients.

    Toru Aoyama, Takaki Yoshikawa, Takafumi Watanabe, Tsutomu Hayashi in Gastric Cancer (2012)

  20. Article

    Macroscopic tumor size as an independent prognostic factor for stage II/III gastric cancer patients who underwent D2 gastrectomy followed by adjuvant chemotherapy with S-1

    In patients with stage II/III gastric cancer, tumors often recur even after curative D2 gastrectomy followed by adjuvant S-1 chemotherapy. The objective of this retrospective study was to clarify the prognosti...

    Toru Aoyama, Takaki Yoshikawa, Takafumi Watanabe, Tsutomu Hayashi in Gastric Cancer (2011)

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