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Article
Open AccessCultural Adaptation of an Evidence-Informed Psychosocial Intervention to Address the Needs of PHIV+ Youth in Thailand
Globally, pediatric HIV has largely become an adolescent epidemic. Thailand has the highest HIV prevalence in Asia (1.2%), with more than 14,000 children living with HIV. There is growing demand for evidence-b...
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Article
Motivational Interviewing Targeting Risky Sex in HIV-Positive Young Thai Men Who Have Sex with Men
Motivational interviewing (MI) has been shown to reduce sexual risks among HIV-positive men who have sex with men (HMSM) in the US. We conducted a randomized trial of Healthy Choices, a 4-session MI interventi...
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Article
Open AccessAssociation between lymphocyte and monocyte subsets and cognition in children with HIV
This study assesses the relationships between lymphocyte and monocyte subsets and intelligence quotient (IQ) scores in antiretroviral therapy (ART)-naive, HIV-infected Thai children without advanced HIV disease.
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Article
Motivational Interviewing Targeting Risk Behaviors for Youth Living with HIV in Thailand
Healthy Choices, a four-session motivational interviewing-based intervention, reduces risk behaviors among US youth living with HIV (YLWH). We randomized 110 Thai YLWH (16–25 years) to receive either Healthy C...
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Article
Open AccessAdherence to Antiretroviral Therapy and Acceptability of Planned Treatment Interruptions in HIV-Infected Children
There have been no paediatric randomised trials describing the effect of planned treatment interruptions (PTIs) of antiretroviral therapy (ART) on adherence, or evaluating acceptability of such a strategy. In ...
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Article
Neurocognitive impairment in patients randomized to second-line lopinavir/ritonavir-based antiretroviral therapy vs. lopinavir/ritonavir monotherapy
We compared rates of neurocognitive impairment (NCI) among 93 Thai adults failing non-nucleoside reverse transcriptase inhibitor (NNRTI)-based combination antiretroviral therapy (cART) before and after switchi...
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Article
Open AccessAssociation of APOBEC3G genotypes and CD4 decline in Thai and Cambodian HIV-infected children with moderate immune deficiency
Human APOBEC3G is a host defense factor that potently inhibits HIV replication. We hypothesize that HIV-infected children with a genetic variant of APOBEC3G will have a more rapid disease progression.
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Article
Open AccessImmunologic and virologic failure after first-line NNRTI-based antiretroviral therapy in Thai HIV-infected children
There are limited data of immunologic and virologic failure in Asian HIV-infected children using non-nucleoside reverse transcriptase inhibitor (NNRTI)-based highly active antiretroviral therapy (HAART). We ex...
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Article
Open AccessA feasibility study of immediate versus deferred antiretroviral therapy in children with HIV infection
To evaluate the feasibility of a large immediate versus deferred antiretroviral therapy (ART) study in children.
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Article
Open AccessUse of taste-masking product, FLAVORx, to assist Thai children to ingest generic antiretrovirals
We evaluated whether FLAVORx helped thirty Thai children take opened capsule, crushed tablets and liquid generic ARVs with more ease. All children had excellent adherence, evaluated by PACTG Standard Internati...
