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Article
Preparation of Thermosensitive Polymer Immobilized Horseradish Peroxidase and its Application in Catalytic Degradation of Phenol
The immobilized horseradish peroxidase (P1-HRP) was prepared based on the affinity interaction between the phenylborate group in mVBA-b-p (AAm co AN) polymer (P1) and the adjacent dihydroxy group in horseradis...
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Article
Herombopag for the treatment of persistent thrombocytopenia following hematopoietic stem cell transplantation
Allogeneic hematopoietic stem cell transplantation (Allo-HSCT) stands as a pivotal treatment for hematologic malignancies, often considered the sole effective treatment option. A frequent complication followin...
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Article
Open AccessSLC27A2 is a potential immune biomarker for hematological tumors and significantly regulates the cell cycle progression of diffuse large B-cell lymphoma
Research on the fatty acid metabolism related gene SLC27A2 is currently mainly focused on solid tumors, and its mechanism of action in hematological tumors has not been reported.
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Article
Performance Assessment of a Novel Polygeneration System Based on the Integration of Waste Plasma Gasification, Tire Pyrolysis, Gas Turbine, Supercritical CO2 Cycle and Organic Rankine Cycle
In this paper, a novel polygeneration system involving plasma gasifier, pyrolysis reactor, gas turbine (GT), supercritical CO2 (S-CO2) cycle, and organic Rankine cycle (ORC) has been developed. In the proposed sc...
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Article
Open AccessChemically programmed STING-activating nano-liposomal vesicles improve anticancer immunity
The often immune-suppressive tumor microenvironment (TME) may hinder immune evasion and response to checkpoint blockade therapies. Pharmacological activation of the STING pathway does create an immunologically...
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Article
Open AccessWnt/beta-catenin signaling confers ferroptosis resistance by targeting GPX4 in gastric cancer
The development of chemotherapy resistance is the most vital obstacle to clinical efficacy in gastric cancer (GC). The dysregulation of the Wnt/beta-catenin signaling pathway is critically associated with GC d...
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Article
Open AccessCombinatorial nanococktails via self-assembling lipid prodrugs for synergistically overcoming drug resistance and effective cancer therapy
Combinatorial systemic chemotherapy is a powerful treatment paradigm against cancer, but it is fraught with problems due to the emergence of chemoresistance and additive systemic toxicity. In addition, coadmin...
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Article
Open AccessCorrection: Photonic-dispersion neural networks for inverse scattering problems
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Article
Open AccessPhotonic-dispersion neural networks for inverse scattering problems
Inferring the properties of a scattering objective by analyzing the optical far-field responses within the framework of inverse problems is of great practical significance. However, it still faces major challe...
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Article
Open AccessA nanomedicine approach enables co-delivery of cyclosporin A and gefitinib to potentiate the therapeutic efficacy in drug-resistant lung cancer
Drug resistance, accounting for therapeutic failure in the clinic, remains a major challenge to effectively manage cancer. Cyclosporin A (CsA) can reverse multidrug resistance (MDR), especially resistance to e...