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    Article

    Preparation of Thermosensitive Polymer Immobilized Horseradish Peroxidase and its Application in Catalytic Degradation of Phenol

    The immobilized horseradish peroxidase (P1-HRP) was prepared based on the affinity interaction between the phenylborate group in mVBA-b-p (AAm co AN) polymer (P1) and the adjacent dihydroxy group in horseradis...

    Yuanyuan Li, Yuanyuan Chen, Tongyu Li, Yongqing Song, Jiacong Wu in Catalysis Letters (2024)

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    Article

    Herombopag for the treatment of persistent thrombocytopenia following hematopoietic stem cell transplantation

    Allogeneic hematopoietic stem cell transplantation (Allo-HSCT) stands as a pivotal treatment for hematologic malignancies, often considered the sole effective treatment option. A frequent complication followin...

    Miao Zhou, Tongyu Li, ** Zhang, Yanli Lai, Lixia Sheng in Annals of Hematology (2024)

  3. Article

    Open Access

    SLC27A2 is a potential immune biomarker for hematological tumors and significantly regulates the cell cycle progression of diffuse large B-cell lymphoma

    Research on the fatty acid metabolism related gene SLC27A2 is currently mainly focused on solid tumors, and its mechanism of action in hematological tumors has not been reported.

    Yi Wang, Xue Chen, Yun Li, Zhixue Zhang, Leiming **a, Jiang Jiang in BMC Medical Genomics (2024)

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    Article

    Performance Assessment of a Novel Polygeneration System Based on the Integration of Waste Plasma Gasification, Tire Pyrolysis, Gas Turbine, Supercritical CO2 Cycle and Organic Rankine Cycle

    In this paper, a novel polygeneration system involving plasma gasifier, pyrolysis reactor, gas turbine (GT), supercritical CO2 (S-CO2) cycle, and organic Rankine cycle (ORC) has been developed. In the proposed sc...

    Fuyuan Feng, Tongyu Li, Jizhen An, Heng Chen, Yi’nan Wang in Journal of Thermal Science (2023)

  5. Article

    Open Access

    Chemically programmed STING-activating nano-liposomal vesicles improve anticancer immunity

    The often immune-suppressive tumor microenvironment (TME) may hinder immune evasion and response to checkpoint blockade therapies. Pharmacological activation of the STING pathway does create an immunologically...

    **aona Chen, Fanchao Meng, Yiting Xu, Tongyu Li, **aolong Chen in Nature Communications (2023)

  6. Article

    Open Access

    Wnt/beta-catenin signaling confers ferroptosis resistance by targeting GPX4 in gastric cancer

    The development of chemotherapy resistance is the most vital obstacle to clinical efficacy in gastric cancer (GC). The dysregulation of the Wnt/beta-catenin signaling pathway is critically associated with GC d...

    Yue Wang, Lixin Zheng, Wen**g Shang, Zongcheng Yang in Cell Death & Differentiation (2022)

  7. Article

    Open Access

    Combinatorial nanococktails via self-assembling lipid prodrugs for synergistically overcoming drug resistance and effective cancer therapy

    Combinatorial systemic chemotherapy is a powerful treatment paradigm against cancer, but it is fraught with problems due to the emergence of chemoresistance and additive systemic toxicity. In addition, coadmin...

    Tongyu Li, Weiwei Shi, Jie Yao, **gyun Hu, Qiong Sun, **g Meng in Biomaterials Research (2022)

  8. Article

    Open Access

    Correction: Photonic-dispersion neural networks for inverse scattering problems

    Tongyu Li, Ang Chen, Lingjie Fan, Minjia Zheng in Light: Science & Applications (2021)

  9. Article

    Open Access

    Photonic-dispersion neural networks for inverse scattering problems

    Inferring the properties of a scattering objective by analyzing the optical far-field responses within the framework of inverse problems is of great practical significance. However, it still faces major challe...

    Tongyu Li, Ang Chen, Lingjie Fan, Minjia Zheng in Light: Science & Applications (2021)

  10. Article

    Open Access

    A nanomedicine approach enables co-delivery of cyclosporin A and gefitinib to potentiate the therapeutic efficacy in drug-resistant lung cancer

    Drug resistance, accounting for therapeutic failure in the clinic, remains a major challenge to effectively manage cancer. Cyclosporin A (CsA) can reverse multidrug resistance (MDR), especially resistance to e...

    Weidong Han, Linlin Shi, Lulu Ren, Liqian Zhou in Signal Transduction and Targeted Therapy (2018)