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  1. Article

    Author Correction: Massively parallel single-cell mitochondrial DNA genoty** and chromatin profiling

    Caleb A. Lareau, Leif S. Ludwig, Christoph Muus, Satyen H. Gohil… in Nature Biotechnology (2023)

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    Article

    Massively parallel single-cell mitochondrial DNA genoty** and chromatin profiling

    Natural mitochondrial DNA (mtDNA) mutations enable the inference of clonal relationships among cells. mtDNA can be profiled along with measures of cell state, but has not yet been combined with the massively p...

    Caleb A. Lareau, Leif S. Ludwig, Christoph Muus, Satyen H. Gohil… in Nature Biotechnology (2021)

  3. No Access

    Article

    Efficient, continuous mutagenesis in human cells using a pseudo-random DNA editor

    Here we describe TRACE (T7 polymerase-driven continuous editing), a method that enables continuous, targeted mutagenesis in human cells using a cytidine deaminase fused to T7 RNA polymerase. TRACE induces high...

    Haiqi Chen, Sophia Liu, Samuel Padula, Daniel Lesman… in Nature Biotechnology (2020)

  4. Article

    Open Access

    CDC42 controls the activation of primordial follicles by regulating PI3K signaling in mouse oocytes

    In mammalian females, progressive activation of dormant primordial follicles in adulthood is crucial for the maintenance of the reproductive lifespan. Misregulated activation of primordial follicles leads to v...

    Hao Yan, Jiawei Zhang, Jia Wen, Yibo Wang, Wanbao Niu, Zhen Teng… in BMC Biology (2018)

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