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  1. No Access

    Article

    Fatty Acid Composition of Plasma, Erythrocytes and Adipose: Their Correlations and Effects of Age and Sex

    The composition of fatty acids in abdominal subcutaneous adipose tissue and the correlation of fatty acid values of plasma and erythrocytes had not been reported in Japan. The aim of the present study was to i...

    Tokuhiro Ogura, Hideho Takada, Masashi Okuno, Hiroaki Kitade, Takashi Matsuura… in Lipids (2010)

  2. No Access

    Article

    The Depressive Effects of 5,8,11-Eicosatrienoic Acid (20:3n-9) on Osteoblasts

    In cases of essential fatty acid deficiency, 5,8,11-eicosatrienoic acid (Mead acid, 20:3n-9) is synthesized from oleic acid as a 20-carbon analog of arachidonic acid. It was reported that 20:3n-9 levels were m...

    Tomohito Hamazaki, Nobuo Suzuki, Retno Widyowati, Tatsuro Miyahara… in Lipids (2009)

  3. No Access

    Article

    n−3 long-chain FA decrease serum levels of TG and remnant-like particle-cholesterol in humans

    A large number of papers have reported that administration of n−3 FA reduced serum TG concentrations in hypertriglyceridemic patients. However, few studies have examined the effect of n−3 FA on serum concentra...

    Kei Hamazaki, Miho Itomura, Mingming Huan, Hiroto Nishizawa, Shiro Watanabe… in Lipids (2003)

  4. No Access

    Article

    Administration of docosahexaenoic acid influences behavior and plasma catecholamine levels at times of psychological stress

    The purpose of the present research was to clarify the effect of docosahexaenoic acid (DHA) intake on behavior and plasma catecholamines (CA). In Study 1, 42 students took either DHA-rich oil capsules containi...

    Tomohito Hamazaki, Shigeki Sawazaki, Tetsuro Nagasawa, Yoko Nagao, Yuko Kanagawa… in Lipids (1999)

  5. No Access

    Article

    Docosahexaenoic acid does not affect aggression of normal volunteers under nonstressful conditions. A randomized, placebo-controlled, double-blind study

    We previously found that docosahexaenoic acid (DHA) intake prevents aggression enhancement at times of mental stress. In the present study we investigated changes in aggression under nonstressful conditions. F...

    Tomohito Hamazaki, Shigeki Sawazaki, Yoko Nagao, Toyomi Kuwamori, Kazunaga Yazawa… in Lipids (1998)

  6. No Access

    Article

    The effects of infusion of trieicosapentaenoyl-glycerol emulsion on extravascular lung water during myocardial ischemia and reperfusion in dogs

    To test the effects of eicosapentaenoic acid (EPA) infusion on pulmonary edema induced by coronary ligation and reperfusion, extravascular lung water (EVLW) was measured in situ by the thermal-dye double indicato...

    Toshio Izuoka, Yutaka Kimura, Tomohito Hamazaki, Teruhiro Tamura, Shuji Kitashiro… in Lipids (1997)

  7. No Access

    Article

    Platelet and aorta arachidonic and eicosapentaenoic acid levels andin vitro eicosanoid production in rats fed high-fat diets

    There is a significant interest in the interrelationship between long-chain n-3, and n-6 fatty acids due to their ability to modulate eicosanoid production. In general, the intake of arachidonic acid (AA) resu...

    Andrew J. Sanigorski, Andrew J. Sinclair, Tomohito Hamazaki in Lipids (1996)

  8. No Access

    Article

    Intravenous injection of tridihomo-γ-linolenoyl-glycerol into mice and its effects on delayed-type hypersensitivity

    Highly purified tridihomo-γ-linolenoyl-glycerol (DGLA-TG) was emulsified with egg yolk lecithin as a 10% (wt/vol) DGLA-TG emulsion. We injected 0.05 or 0.5 mL of the emulsion into mice through the tail vein an...

    Hirofumi Taki, Norio Nakamura, Tomohito Hamazaki, Masashi Kobayashi in Lipids (1993)

  9. No Access

    Article

    Reduction in microalbuminuria in diabetics by eicosapentaenoic acid ethyl ester

    Eicosapentaenoic acid (EPA) ethyl ester (1.8 g/d) was administered to 16 diabetic patients (5 insulin-dependent and 11 noninsulin-dependent diabetics) for 6 mon. EPA in total plasma fatty acids increased from ...

    Tomohito Hamazaki, Eisuke Takazakura, Kenzo Osawa, Masaharu Urakaze, Saburo Yano in Lipids (1990)

  10. No Access

    Article

    Effect of eicosapentaenoic acid ethyl ester on proteinuria of streptozotocin-induced diabetes mellitus in rats

    Streptozotocin (45 mg/kg) was intravenously administered to 7-week-old Wistar rats through their tail veins. After 11 days, the rats were divided into two groups. One group was fed a lipid-free diet (90%, w/w)...

    Mariko Fujikawa, Katsuya Yamazaki, Shigeki Sawazaki, Hirofumi Taki, Mariko Kaneda… in Lipids (1989)

  11. No Access

    Article

    Injection of tridocosahexaenoyl-glycerol emulsion and fatty acid composition of blood cells

    An injectable emulsion of docosahexaenoic acid (DHA) was prepared. One hundred ml of the emulsion contained 3 g of 93%-pure 1,2,3-tridocosahexaenoylglycerol (DHA-TG), 1.2 g of 93%-pure 2-docosahexaenoyl-phosph...

    Tomohito Hamazaki, Masaharu Urakaze, Saburo Yano, Yasuji Soda, Akira Miyamoto… in Lipids (1987)

  12. No Access

    Article

    Intake of different eicosapentaenoic acid-containing lipids and fatty acid pattern of plasma lipids in the rats

    The ethyl ester of eicosapentaenoic acid (EPA) is the only pure EPA-containing lipid available in bulk for oral administration. However, there is doubt as to whether EPA ethyl ester can efficiently increase th...

    Tomohito Hamazaki, Masaharu Urakaze, Masahiro Makuta, Akio Ozawa, Yasuji Soda… in Lipids (1987)