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Open AccessProspective evaluation of core number of biopsy for renal tumor: are multiple cores preferable?
This single-center, single-arm, prospective, open-label study was conducted to evaluate the optimal number of cores (single or multiple) in renal tumor biopsy.
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Article
Correction to: Periostin secreted by cancer‑associated fibroblasts promotes cancer progression and drug resistance in non‑small cell lung cancer
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Periostin secreted by cancer-associated fibroblasts promotes cancer progression and drug resistance in non-small cell lung cancer
Cancer-associated fibroblasts (CAFs) are important components in the tumor microenvironment, and we sought to identify effective therapeutic targets in CAFs for non-small cell lung cancer (NSCLC). In this stud...
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Article
Open AccessRegulatory T cells induce a suppressive immune milieu and promote lymph node metastasis in intrahepatic cholangiocarcinoma
Emerging evidence indicates that immunogenicity plays an important role in intrahepatic cholangiocarcinoma (ICC). Herein, we systematically evaluated the clinical relevance of immunogenicity in ICC.
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Article
Chronic active Epstein–Barr virus infection presenting as refractory chronic sinusitis
A 44-year-old Japanese man presented with fever and sore throat. He had a history of refractory chronic sinusitis that did not respond to several years of pharmacotherapy, and underwent endoscopic sinus surger...
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Article
Correction to: PD-L1 expression in tongue squamous cell carcinoma
In the original publication of the article an affiliation should be added to the first author “Naoki Akisada” as given below.
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Article
PD-L1 expression in tongue squamous cell carcinoma
Immune checkpoint proteins programmed cell death 1 (PD-1) and programmed cell death ligand 1 (PD-L1) are important therapeutic targets for head and neck cancer. This large-scale case study aimed to analyze ton...
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Article
The neutrophil-to-lymphocyte ratio as a novel independent prognostic factor for multiple metastatic lung tumors from various sarcomas
Sarcomas are among the most refractory malignant tumors and often recur as pulmonary metastasis. Although the presence of a high neutrophil-to-lymphocyte ratio (NLR) has been associated with the prognosis of s...
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Article
Open AccessA case report of TAFRO syndrome successfully treated by immunosuppressive therapies with plasma exchange
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Article
Open AccessElevation of serum interleukins 8, 4 and 1β levels in patients with gastrointestinal low-grade B-cell lymphoma
Proinflammatory cytokines that are produced by helper T cells (Th) regulate immune reactions, facilitate class switching of B cells and prolong the lifespan of B and T cells. Eradication therapy using antibiot...
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Article
In aggressive variants of non-Hodgkin lymphomas, Ezh2 is strongly expressed and polycomb repressive complex PRC1.4 dominates over PRC1.2
Polycomb group (PcG) proteins are important for the regulation of hematopoiesis by regulating chromatin compaction and silencing genes related to differentiation and cell cycle. Overexpression of enhancer of z...
