27 Result(s)

Chapter and Conference Paper

Bidirectional Loading Test of Buckling-Restrained Braces with Gusset Plate Connections

Buckling-restrained braces (BRBs) are a type of seismic device and are employed in steel moment-resisting frames and other building and civil engineering structures. Previous studies have examined the behavior...

Yuji Koetaka, Yuki Tamura, Ryota Tobari… in Proceedings of the 11th International Conf… (2024)

Article

Efficacy and safety of obinutuzumab in patients with previously untreated follicular lymphoma: a subgroup analysis of patients enrolled in Japan in the randomized phase III GALLIUM trial

GALLIUM is a global phase III study that demonstrated a statistically significant and clinically meaningful improvement in progression-free survival (PFS) with obinutuzumab plus chemotherapy (G-chemo) versus r...

Ken Ohmachi, Kensei Tobinai, Tomohiro Kinoshita… in International Journal of Hematology (2018)

Article

Bendamustine plus rituximab for previously untreated patients with indolent B-cell non-Hodgkin lymphoma or mantle cell lymphoma: a multicenter Phase II clinical trial in Japan

A Phase II, multicenter clinical trial of bendamustine plus rituximab (BR) regimen was conducted in previously untreated patients with high-tumor-burden indolent B-cell non-Hodgkin lymphoma (B-NHL) and previou...

Michinori Ogura, Kenichi Ishizawa, Dai Maruyama… in International Journal of Hematology (2017)

Article

Prediction of high risk for death in patients with follicular lymphoma receiving rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisolone in first-line chemotherapy

Risk stratification of patients with relapsed and refractory follicular lymphoma (FL) remains challenging. Recently, much attention has been paid to the impact of early progression of disease within 2 years of...

Satsuki Murakami, Harumi Kato, Yusuke Higuchi, Kazuhito Yamamoto… in Annals of Hematology (2016)

Article

Proposed diagnostic criteria, disease severity classification and treatment strategy for TAFRO syndrome, 2015 version

TAFRO syndrome is a systemic inflammatory disorder characterized by thrombocytopenia, anasarca including pleural effusion and ascites, fever, renal insufficiency, and organomegaly including hepatosplenomegaly ...

Yasufumi Masaki, Hiroshi Kawabata, Kazue Takai… in International Journal of Hematology (2016)

Article

Phase I dose-escalation study of cyclophosphamide combined with bortezomib and dexamethasone in Japanese patients with relapsed and/or refractory multiple myeloma

The present study was conducted to determine the recommended dose (RD) of cyclophosphamide (CPM) in the CBD regimen, a triplet combination of CPM, bortezomib (BTZ), and dexamethasone (Dex), for relapsed and/or...

Isamu Sugiura, Satomi Terabe, Tomohiro Kinoshita… in International Journal of Hematology (2015)

Article

Salvage therapy with single agent L-asparaginase followed by local irradiation in an elderly patient with CD56-positve primary isolated extramedullary T-cell lymphoblastic lymphoma of the sinus

Daiki Hirano, Harumi Kato, Takeshi Kodaira, Yasushi Yatabe… in Annals of Hematology (2015)

Article

Phase II study of cyclophosphamide, doxorubicin, vincristine, prednisolone (CHOP) therapy for newly diagnosed patients with low- and low–intermediate risk, aggressive non-Hodgkin’s lymphoma: final results of the Japan Clinical Oncology Group Study, JCOG9508

The regimen of cyclophosphamide, doxorubicin, vincristine, and prednisolone, known as CHOP therapy, has been established as the standard treatment for aggressive non-Hodgkin’s lymphoma (NHL). Although patients...

Yoshitoyo Kagami, Kuniaki Itoh, Kensei Tobinai… in International Journal of Hematology (2012)

Article

Retrospective analysis of primary gastric diffuse large B cell lymphoma in the rituximab era: a multicenter study of 95 patients in Japan

Primary gastric diffuse large B cell lymphoma (PG-DLBCL) is common subtype of extranodal non-Hodgkin lymphoma. The optimal treatment strategy for PG-DLBCL in the rituximab era still remains unknown. To evaluat...

Tsutomu Tanaka, Kazuyuki Shimada, Kazuhito Yamamoto… in Annals of Hematology (2012)

Article

Phase II study of ABVd therapy for newly diagnosed clinical stage II–IV Hodgkin lymphoma: Japan Clinical Oncology Group study (JCOG 9305)

Although ABVD (doxorubicin, bleomycin, vinblastine and dacarbazine) therapy has been regarded as a standard of care for advanced-stage Hodgkin lymphoma (HL) since 1992, there has been no prospective data of AB...

Michinori Ogura, Kuniaki Itoh, Tomohiro Kinoshita… in International Journal of Hematology (2010)

Article

Prognostic analysis and a new risk model for Hodgkin lymphoma in Japan

The Japan Clinical Oncology Group conducted two multicenter phase II trials in 200 patients with advanced Hodgkin lymphoma (HL) in the 1990s. Among 181 patients whose histopathological specimens were available...

Kuniaki Itoh, Tomohiro Kinoshita, Takashi Watanabe… in International Journal of Hematology (2010)

Article

Evaluation of organ involvement in intravascular large B-cell lymphoma by ¹⁸F-fluorodeoxyglucose positron emission tomography

To evaluate the role of ¹⁸F-fluorodeoxyglucose positron emission tomography (FDG-PET) in intravascular large B-cell lymphoma (IVLBCL), we retrospectively analyzed four consecutive IVLBCL patients receiving FDG-PE...

Kazuyuki Shimada, Hiroshi Kosugi, Satoko Shimada… in International Journal of Hematology (2008)

Article

Epigenetic Regulation of CD20 Protein Expression in a Novel B-Cell Lymphoma Cell Line, RRBL1, Established from a Patient Treated Repeatedly with Rituximab-Containing Chemotherapy

Rituximab is a chimeric monoclonal antibody to the surface antigen CD20 and has provided better outcomes against CD20⁺ B-cell lymphomas than chemotherapy with conventional antitumor drugs alone. Treatment with ri...

Akihiro Tomita, Junji Hiraga, Hitoshi Kiyoi… in International Journal of Hematology (2007)

Article

Loss of O ⁶-Methylguanine-DNA Methyltransferase Protein Expression Is a Favorable Prognostic Marker in Diffuse Large B-Cell Lymphoma

Although aberrant promoter hypermethylation of O ⁶-methylguanine-DNA methyltransferase (MGMT) is a favorable prognostic marker in patients with diffuse large B-cell lymphoma (DLBCL), MGMT protein expression has n...

Toshihito Ohno, Junji Hiraga, Haruhiko Ohashi… in International Journal of Hematology (2006)

Article

A Case of Interstitial Pneumonia Induced by Rituximab Therapy

Junji Hiraga, Yasuhiro Kondoh, Hiroyuki Taniguchi… in International Journal of Hematology (2005)

Article

A Randomized Controlled Trial Investigating the Survival Benefit of Dose-Intensified Multidrug Combination Chemotherapy (LSG9) for Intermediate- or High-Grade Non-Hodgkin’s Lymphoma: Japan Clinical Oncology Group Study 9002

The effect of enhancing the dose intensity (DI) of the key drugs in multidrug combination chemotherapy for malignant lymphoma is uncertain. We investigated the survival benefit of dose-intensified multidrug co...

Tomohiro Kinoshita, Tomomitsu Hotta, Kensei Tobinai… in International Journal of Hematology (2004)

Article

Epigenetic Inactivation of Tumor Suppressor Genes in Hematologic Malignancies

A number of genetic alterations are involved in the development of hematologic malignancies. These alterations include the activation of oncogenes by chromosomal translocation or gene amplification and the ina...

Tomohiro Kinoshita in International Journal of Hematology (2004)