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Article
Open AccessMolecular and cellular basis of acid taste sensation in Drosophila
Acid taste, evoked mainly by protons (H+), is a core taste modality for many organisms. The hedonic valence of acid taste is bidirectional: animals prefer slightly but avoid highly acidic foods. However, how anim...
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Article
Open AccessPrecisely controlling endogenous protein dosage in hPSCs and derivatives to model FOXG1 syndrome
Dosage of key regulators im**e on developmental disorders such as FOXG1 syndrome. Since neither knock-out nor knock-down strategy assures flexible and precise protein abundance control, to study hypomorphic ...