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  1. No Access

    Article

    STING signaling remodels the tumor microenvironment by antagonizing myeloid-derived suppressor cell expansion

    Stimulator of interferon genes (STING), a major adaptor protein in antiviral innate immune signaling, is considered as one of the most important regulators of antiviral and antitumor immunity. Although STING a...

    Chuan-xia Zhang, Shu-biao Ye, Jian-jiao Ni, Ting-ting Cai… in Cell Death & Differentiation (2019)

  2. Article

    Open Access

    Sphingosine 1 phosphate receptor-1 (S1P1) promotes tumor-associated regulatory T cell expansion: leading to poor survival in bladder cancer

    Regulatory T cells (Tregs) represent an important contributor to cancer immune escape, but the molecular mechanism responsible for Treg expansion in tumors is heterogeneous and unclear. Here, we investigated t...

    Yi-Na Liu, Han Zhang, Lin Zhang, Ting-Ting Cai, Dai-Jia Huang… in Cell Death & Disease (2019)

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