53 Result(s)

Article

A genome-wide association study reveals novel loci and candidate genes associated with plant height variation in Medicago sativa

Plant height (PH) is an important agronomic trait influenced by a complex genetic network. However, the genetic basis for the variation in PH in Medicago sativa remains largely unknown. In this study, a comprehen...

Xueqian Jiang, Tianhui Yang, Fei He, Fan Zhang, Xu Jiang, Chuan Wang… in BMC Plant Biology (2024)

Article

Molecular characterization of m6A RNA methylation regulators with features of immune dysregulation in IgA nephropathy

The role of RNA N6-methyladenosine (m6A) modification in immunity is being elucidated. This study aimed to explore the potential association between m6A regulators and the immune microenvironment in IgA nephro...

Yihao Wang, Nan Sun, Rui He, Zida Wang, **gsi **… in Clinical and Experimental Medicine (2024)

Article

Circ_0087851 suppresses colorectal cancer malignant progression through triggering miR-593-3p/BAP1-mediated ferroptosis

Emerging research has validated that circular RNAs (circRNAs) have indispensable regulatory functions in tumorigenesis, including colorectal cancer (CRC). Ferroptosis is a specific cell death form and implicat...

Ming Huang, Ting Gao, **anyong Chen… in Journal of Cancer Research and Clinical On… (2024)

Article

Genome-wide identification, characterization and expression of C2H2 zinc finger gene family in Opisthopappus species under salt stress

The C2H2 zinc finger protein family plays important roles in plants. However, precisely how C2H2s function in Opisthopappus (Opisthopappus taihangensis and Opisthopappus longilobus) remains unclear.

**aojuan Zhou, Ting Gao, Yimeng Zhang, Mian Han, Yuexin Shen, Yu Su… in BMC Genomics (2024)

Article

Multi-type concept drift detection under a dual-layer variable sliding window in frequent pattern mining with cloud computing

The detection of different types of concept drift has wide applications in the fields of cloud computing and security information detection. Concept drift detection can indeed assist in promptly identifying in...

**g Chen, Shengyi Yang, Ting Gao, Yue Ying, Tian Li, Peng Li in Journal of Cloud Computing (2024)

Article

Systemic metabolic engineering of Enterobacter aerogenes for efficient 2,3-butanediol production

2,3-Butanediol (2,3-BDO) is an important gateway molecule for many chemical derivatives. Currently, microbial production is gradually being recognized as a green and sustainable alternative to petrochemical sy...

** Lu, Ruoxuan Bai, Ting Gao, Jiale Chen… in Applied Microbiology and Biotechnology (2024)

Article

Author Correction: Two distinct trajectories of clinical and neurodegeneration events in Parkinson’s disease

Cheng Zhou, Linbo Wang, Wei Cheng, **Chao Lv, **aojun Guan… in npj Parkinson's Disease (2024)

Article

Engineered poly(A)-surrogates for translational regulation and therapeutic biocomputation in mammalian cells

Here, we present a gene regulation strategy enabling programmable control over eukaryotic translational initiation. By excising the natural poly-adenylation (poly-A) signal of target genes and replacing it wit...

Jiawei Shao, Shichao Li, **nyuan Qiu, Jian Jiang, Lihang Zhang… in Cell Research (2024)

Article

Metagenome-wide analysis uncovers gut microbial signatures and implicates taxon-specific functions in end-stage renal disease

The gut microbiota plays a crucial role in regulating host metabolism and producing uremic toxins in patients with end-stage renal disease (ESRD). Our objective is to advance toward a holistic understanding of...

Pan Zhang, **fan Wang, Shenghui Li, Xuesen Cao, Jianzhou Zou, Yi Fang… in Genome Biology (2023)

Article

Nomogram for predicting survival in patients with mucinous breast cancer undergoing chemotherapy and surgery: a population-based study

The prognosis of patients with mucinous breast cancer (MuBC) is affected by several factors, but the low incidence of MuBC makes it difficult to conduct extensive and in-depth studies. This study was designed ...

Ting Gao, Yuyuan Chen, Ming Li, Keying Zhu… in European Journal of Medical Research (2023)

Article

Optimization of hydrogen production in Enterobacter aerogenes by Complex I peripheral fragments destruction and maeA overexpression

As a concentrated energy source with high added value, hydrogen has great development prospects, with special emphasis on sustainable microbial production as a replacement for traditional fossil fuels. In this...

Ke Jiang, Ruoxuan Bai, Ting Gao, ** Lu, **gya Zhang… in Microbial Cell Factories (2023)

Article

Two distinct trajectories of clinical and neurodegeneration events in Parkinson’s disease

Increasing evidence suggests that Parkinson’s disease (PD) exhibits disparate spatial and temporal patterns of progression. Here we used a machine-learning technique—Subtype and Stage Inference (SuStaIn) — to ...

Cheng Zhou, Linbo Wang, Wei Cheng, **Chao Lv, **aojun Guan… in npj Parkinson's Disease (2023)

Article

Overexpression of the elongation factor MtEF1A1 promotes salt stress tolerance in Arabidopsis thaliana and Medicago truncatula

Elongation factor 1 A (EF1A), an essential regulator for protein synthesis, has been reported to participate in abiotic stress responses and environmental adaption in plants. However, the role of EF1A in abiotic ...

Lei Xu, Lixia Zhang, Yajiao Liu, Bilig Sod, Mingna Li, Tianhui Yang… in BMC Plant Biology (2023)

Article

Landscape analysis of m6A modification regulators related biological functions and immune characteristics in myasthenia gravis

N6-methyladenosine (m6A) modification has been recognized to play fundamental roles in the development of autoimmune diseases. However, the implication of m6A modification in myasthenia gravis (MG) remains lar...

Shuang Li, Hui Liu, Zhe Ruan, Rong**g Guo, Chao Sun… in Journal of Translational Medicine (2023)

Article

GlPS1 overexpression accumulates coumarin secondary metabolites in transgenic Arabidopsis

The dried root of Glehnia littoralis is a traditional Chinese herbal medicine mainly used to treat lung diseases and plays an important role in fighting coronavirus disease 2019 pneumonia in China. This study foc...

Hongwei Ren, Yanchong Yu, Yao Xu… in Plant Cell, Tissue and Organ Culture (PCTO… (2023)

Article

Correction to: A cobalt oxide@polydopamine-reduced graphene oxide-based 3D photothermal evaporator for highly efficient solar steam generation

The original article can be found online.

Ting Gao, Xuan Wu, Gary Owens, Hao-Lan Xu in Tungsten (2022)

Article

Microstructural but not macrostructural cortical degeneration occurs in Parkinson’s disease with mild cognitive impairment

This study aimed to investigate the cortical microstructural/macrostructural degenerative patterns in Parkinson’s disease (PD) patients with mild cognitive impairment (MCI). Overall, 38 PD patients with normal...

Xueqin Bai, Tao Guo, **gwen Chen, **aojun Guan, Cheng Zhou… in npj Parkinson's Disease (2022)

Article

Combining QTL map** and RNA-Seq Unravels candidate genes for Alfalfa (Medicago sativa L.) leaf development

Leaf size affects crop canopy morphology and photosynthetic efficiency, which can influence forage yield and quality. It is of great significance to mine the key genes controlling leaf development for breeding...

Xueqian Jiang, **jiang Yang, Fan Zhang, Tianhui Yang, Changfu Yang… in BMC Plant Biology (2022)

Article

Highly pathogenic coronavirus N protein aggravates inflammation by MASP-2-mediated lectin complement pathway overactivation

Excessive inflammatory responses contribute to the pathogenesis and lethality of highly pathogenic human coronaviruses, but the underlying mechanism remains unclear. In this study, the N proteins of highly pat...

Ting Gao, Lin Zhu, Hainan Liu, **aopeng Zhang… in Signal Transduction and Targeted Therapy (2022)

Article

Improved indirect limits on charm and bottom quark EDMs

We derive indirect limits on the charm and bottom quark electric dipole moments (EDMs) from paramagnetic AMO and neutron EDM experiments. The charm and bottom quark EDMs generate CP-odd photon-gluon operators and...

Yohei Ema, Ting Gao, Maxim Pospelov in Journal of High Energy Physics (2022)