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Article
Grand challenges in bioinformatics education and training
With the increasing need for bioinformatics expertise in the life sciences, a coordinated effort is needed to proactively and critically reflect on the challenges of educating and training life scientists with...
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Article
The Singapore National Precision Medicine Strategy
Precision medicine promises to transform healthcare for groups and individuals through early disease detection, refining diagnoses and tailoring treatments. Analysis of large-scale genomic–phenotypic databases...
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Open AccessA multi-task CNN learning model for taxonomic assignment of human viruses
Taxonomic assignment is a key step in the identification of human viral pathogens. Current tools for taxonomic assignment from sequencing reads based on alignment or alignment-free k-mer approaches may not perfor...
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Article
Open AccessTowards precision medicine: interrogating the human genome to identify drug pathways associated with potentially functional, population-differentiated polymorphisms
Drug response variations amongst different individuals/populations are influenced by several factors including allele frequency differences of single nucleotide polymorphisms (SNPs) that functionally affect dr...
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Article
Open AccessAnalysis of viral diversity for vaccine target discovery
Viral vaccine target discovery requires understanding the diversity of both the virus and the human immune system. The readily available and rapidly growing pool of viral sequence data in the public domain ena...
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Open AccessExploring the transcriptome of non-model oleaginous microalga Dunaliella tertiolecta through high-throughput sequencing and high performance computing
RNA-Seq technology has received a lot of attention in recent years for microalgal global transcriptomic profiling. It is widely used in transcriptome-wide analysis of gene expression., particularly for microal...
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Protocol
T-Cell Epitope Prediction of Chikungunya Virus
There has been a growing demand for vaccines against Chikungunya virus (CHIKV), and epitope-based vaccine is a promising solution. Identification of CHIKV T-cell epitopes is critical to ensure successful trigg...
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Open AccessGIW and InCoB are advancing bioinformatics in the Asia-Pacific
GIW/InCoB2015 the joint 26th International Conference on Genome Informatics (GIW) and 14th International Conference on Bioinformatics (InCoB) held in Tokyo, September 9-11, 2015 was attended by over 200 delega...
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Article
Open AccessGIW and InCoB, two premier bioinformatics conferences in Asia with a combined 40 years of history
Knowledge discovery in bioinformatics thrives on joint and inclusive efforts of stakeholders. Similarly, knowledge dissemination is expected to be more effective and scalable through joint efforts. Therefore, ...
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Article
Open AccessRNA-Seq transcriptomic analysis with Bag2D software identifies key pathways enhancing lipid yield in a high lipid-producing mutant of the non-model green alga Dunaliella tertiolecta
For many years, increasing demands for fossil fuels have met with limited supply. As a potential substitute and renewable source of biofuel feedstock, microalgae have received significant attention. However, f...
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Protocol
Building MHC Class II Epitope Predictor Using Machine Learning Approaches
Identification of T-cell epitopes binding to MHC class II molecules is an important step in epitope-based vaccine development. This process has since been accelerated with the use of bioinformatics tools to ai...
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Article
Open AccessInCoB2014: bioinformatics to tackle the data to knowledge challenge
Since 2006, the International Conference on Bioinformatics (InCoB) has been publishing selected papers in BMC Bioinformatics. Papers within the scope of the journal from the 13th InCoB July 31-2 August, 2014 i...
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Open AccessInCoB2014: mining biological data from genomics for transforming industry and health
The 13th International Conference on Bioinformatics (InCoB2014) was held for the first time in Australia, at Sydney, July 31-2 August, 2014. InCoB is the annual scientific gathering of the Asia-Pacific Bioinfo...
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Open AccessInCoB2014: Systems Biology update from the Asia-Pacific
Selected papers from the 13th International Conference on Bioinformatics (InCoB2014), July 31-2 August, 2014 in Sydney, Australia have been compiled in this supplement. These range from network analysis and ge...
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Article
Open AccessPredicting host tropism of influenza A virus proteins using random forest
Majority of influenza A viruses reside and circulate among animal populations, seldom infecting humans due to host range restriction. Yet when some avian strains do acquire the ability to overcome species barr...
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Protocol
Structure-Based Clustering of Major Histocompatibility Complex (MHC) Proteins for Broad-Based T-Cell Vaccine Design
Structure-based clustering technique is useful for identifying superfamilies of major histocompatibility complex (MHC) proteins with similar binding specificities. The resolved MHC superfamilies play an import...
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Article
Open AccessInCoB2013 introduces Systems Biology as a major conference theme
The Asia-Pacific Bioinformatics Network (APBioNet) held the first International Conference on Bioinformatics (InCoB) in Bangkok in 2002 to promote North-South networking. Commencing as a forum for Asia-Pacific...
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Article
Open AccessSimple re-instantiation of small databases using cloud computing
Small bioinformatics databases, unlike institutionally funded large databases, are vulnerable to discontinuation and many reported in publications are no longer accessible. This leads to irreproducible scienti...
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Article
Open AccessAdvances in translational bioinformatics and population genomics in the Asia-Pacific
The theme of the 2012 International Conference on Bioinformatics (InCoB) in Bangkok, Thailand was "From Biological Data to Knowledge to Technological Breakthroughs." Besides providing a forum for life scientis...
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Article
Open AccessInCoB2012 Conference: from biological data to knowledge to technological breakthroughs
Ten years ago when Asia-Pacific Bioinformatics Network held the first International Conference on Bioinformatics (InCoB) in Bangkok its theme was North-South Networking. At that time InCoB aimed to provide bio...
