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Article
Factors associated with the melanoma diagnostic interval in Ontario, Canada: a population-based study
Protracted times to diagnosis of cancer can lead to increased patient anxiety, and in some cases, disease progression and worse outcomes. This study assessed the time to diagnosis for melanoma, and its variabi...
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Article
Open AccessA perspective on life-cycle health technology assessment and real-world evidence for precision oncology in Canada
Health technology assessment (HTA) can be used to make healthcare systems more equitable and efficient. Advances in precision oncology are challenging conventional thinking about HTA. Precision oncology advanc...
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Article
Open AccessA population-based validation study of the 8th edition UICC/AJCC TNM staging system for cutaneous melanoma
The 8th edition UICC/AJCC TNM8 (Tumour, Nodes, Metastasis) melanoma staging system introduced several modifications from the 7th edition (TNM7), resulting in changes in survival and subgroup composition. We set o...
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Article
Open AccessCancer staging in individuals with a severe psychiatric illness: a cross-sectional study using population-based cancer registry data
Advanced cancer stage at diagnosis may explain high cancer mortality among patients with a severe psychiatric illness (SPI). Studies to date investigating advanced stage cancer at diagnosis as a potential expl...
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Article
Cancer, COVID-19 and the precautionary principle: prioritizing treatment during a global pandemic
During the COVID-19 global pandemic, the cancer community faces many difficult questions. We will first discuss safety considerations for patients with cancer requiring treatment in SARS-CoV-2 endemic areas. W...
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Article
Open AccessReal-world comparative effectiveness of second-line ipilimumab for metastatic melanoma: a population-based cohort study in Ontario, Canada
For novel cancer treatments, effectiveness in clinical practice is not always aligned with clinical efficacy results. As such it is important to understand a treatment’s real-world effectiveness. We examined r...
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Article
Open AccessCancer control in develo** countries: using health data and health services research to measure and improve access, quality and efficiency
Cancer is a rapidly increasing problem in develo** countries. Access, quality and efficiency of cancer services in develo** countries must be understood to advance effective cancer control programs. Health...