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Open AccessAortic elastic fiber degeneration during acute type a aortic dissection and reverse aortic remodeling
Progression of proximal or distal aortic dilatation is defined as reverse aortic remodeling after surgery for acute type A aortic dissection (ATAAD) that may be dependent on aortic wall degeneration.
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Article
Open AccessHistopathology reveals concealed aortic valve inflammation
The extent of aortic valve inflammation in patients undergoing aortic valve replacement (AVR) is unsettled. The significance of aortic valve histopathology in patients undergoing AVR is undetermined.
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Article
Open AccessAscending aortic wall degeneration in patients with bicuspid versus tricuspid aortic valve
The magnitude of ascending aortic degeneration in patients with bicuspid aortic valves (BAV) is controversial.
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Open AccessEvaluation Challenges in the Validation of B7-H3 as Oral Tongue Cancer Prognosticator
B7-H3 was the only molecule identified with prognostic potential from a recent systematic review of the prognostic value of immune checkpoints in oral cancer. We aimed to validate this finding in a multicenter...
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Article
Open AccessClinicopathological features and prognostic value of SOX11 in childhood acute lymphoblastic leukemia
Acute lymphoblastic leukemia is marked by aberrant transcriptional features that alter cell differentiation, self-renewal, and proliferative features. We sought to identify the transcription factors exhibiting...
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Article
Open AccessPerformance of Finnish biobanks in nationwide pulmonary carcinoid tumour research
Finnish hospital-integrated biobanks administer millions of formalin-fixed paraffin-embedded tissue samples collected within the clinical diagnostics. According to the Finnish Biobank Act, these samples can be...
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Article
Open AccessEndothelin A receptor blocker and calcimimetic in the adenine rat model of chronic renal insufficiency
We studied whether endothelin receptor antagonist and calcimimetic treatments influence renal damage and kidney renin-angiotensin (RA) components in adenine-induced chronic renal insufficiency (CRI).
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Article
Open AccessBronchoalveolar lavage in infants with recurrent lower respiratory symptoms
Few data are available about the inflammatory cytokine profile of bronchoalveolar lavage (BAL) from young children with frequent wheeze. The first aim was to investigate the BAL cellular and cytokine profiles ...
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Article
Open AccessPolysialic acid is associated with better prognosis and IDH1-mutation in diffusely infiltrating astrocytomas
The aim of the study was to assess the localization of Polysialic acid (polySia) and Neural cell adhesion molecule (NCAM) in grade I–IV astrocytomas by confocal microscopy, and also to clarify and compare thei...
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Article
Open AccessComplement activation in astrocytomas: deposition of C4d and patient outcome
C4d is a cleavage product of complement component C4 and is considered to serve as a marker for the site of complement activation. In this study C4d staining of grade I-IV astrocytic tumors was studied to expl...
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Article
Open AccessIndoleamine 2,3-dioxygenase expression in patients with allergic rhinitis: a case-control study
Indoleamine 2,3-dioxygenase (IDO) is a tryptophan catalyzing enzyme. It has been suggested that it has a role in lower airway allergic inflammations, but its role in allergic rhinitis has not been investigated.