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Article
Open AccessLong-term effects of aromatase inhibitor withdrawal on bone mineral density in early breast cancer patients: 10-year follow-up results of the BREX study
We aimed to provide long-term bone mineral density (BMD) data on early breast cancer patients of the BREX (Breast Cancer and Exercise) study. The effects of exercise and adjuvant endocrine treatment 10 years a...
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Article
Open AccessChemoradiation for oesophageal cancer: the choice of treatment modality
Locally advanced oesophageal cancer can be treated with definitive chemoradiation (dCRT) or with neoadjuvant chemoradiation followed by surgery (nCRT + S), but treatment modality choice is not always clear. Th...
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Article
Open AccessEffect of palliative care decisions making on hospital service use at end-of-life in patients with malignant brain tumors: a retrospective study
Palliative care (PC) improves Quality of life and reduces the symptom burden. Aggressive treatments at end of life (EOL) postpone PC. The aim of this single-center retrospective study was to evaluate the timin...
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Article
Open AccessMindfulness is associated with improved psychological well-being but no change in stress biomarkers in breast cancer survivors with depression: a single group clinical pilot study
The aim of this clinical single group pilot study was to assess mental well-being, psychological symptoms, and a set of stress biomarkers among breast cancer survivors with high depressive symptoms undergoing ...
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Article
Open AccessA graphical LASSO analysis of global quality of life, sub scales of the EORTC QLQ-C30 instrument and depression in early breast cancer
We aimed to (a) investigate the interplay between depression, symptoms and level of functioning, and (b) understand the paths through which they influence health related quality of life (QOL) during the first ...
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Article
Open AccessA Nordic survey of the management of palliative care in patients with head and neck cancer
The five Nordic countries with a population of 27M people form a rather homogenous region in terms of health care. The management of Head and Neck Cancer (HNC) is centralized to the 21 university hospitals in ...
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Article
Open AccessThe required competencies of physicians within palliative care from the perspectives of multi-professional expert groups: a qualitative study
Although statements on the competencies required from physicians working within palliative care exist, these requirements have not been described within different levels of palliative care provision by multi-p...
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Article
Open AccessThe impact of the duration of the palliative care period on cancer patients with regard to the use of hospital services and the place of death: a retrospective cohort study
In order to avoid unnecessary use of hospital services at the end-of-life, palliative care should be initiated early enough in order to have sufficient time to initiate and carry out good quality advance care ...
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Article
Automatic referral to standardize palliative care access: an international Delphi survey
Palliative care referral is primarily based on clinician judgment, contributing to highly variable access. Standardized criteria to trigger automatic referral have been proposed, but it remains unclear how bes...
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Article
Open AccessUndergraduate curriculum in palliative medicine at Tampere University increases students’ knowledge
Education in palliative medicine (PM) at medical schools reveals wide variation despite the increasing importance of palliative care. Many universities present poor description of the benefits and detailed con...
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Article
Health-related quality of life among breast, prostate, and colorectal cancer patients with end-stage disease
To explore end-stage breast, prostate, and colorectal cancer patients’ health-related quality of life (HRQoL); to compare results obtained by different HRQoL instruments; and to explore factors related to impa...
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Article
Burden of chemotherapy-induced neuropathy—a cross-sectional study
Neuropathy is a common adverse effect of chemotherapy. However, the both the prevalence and the burden of this adverse effect have been poorly documented. The aim of the study was to assess the prevalence and ...
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Adjuvant Therapy of Breast Cancer – Bisphosphonates
The skeleton is a first site of recurrence in every third relapse in breast cancer. Approximately 705 (50–80%) of metastatic breast cancer patients have bone metastases [1]. Bisphosphonates have been used succ...
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Article
Short-Term Intermittent Intravenous Clodronate in the Prevention of Bone Loss Related to Chemotherapy-Induced Ovarian Failure
Chemotherapy-induced ovarian failure causes rapid bone loss in premenopausal women with early breast cancer. The aim of the present study was to investigate the effect of intravenous intermittent clodronate du...
