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Article
Open AccessAssociation of post-COVID phenotypic manifestations with new-onset psychiatric disease
Acute COVID-19 infection can be followed by diverse clinical manifestations referred to as Post Acute Sequelae of SARS-CoV2 Infection (PASC). Studies have shown an increased risk of being diagnosed with new-on...
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Article
Open AccessAn open source knowledge graph ecosystem for the life sciences
Translational research requires data at multiple scales of biological organization. Advancements in sequencing and multi-omics technologies have increased the availability of these data, but researchers face s...
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Article
Open AccessGRAPE for fast and scalable graph processing and random-walk-based embedding
Graph representation learning methods opened new avenues for addressing complex, real-world problems represented by graphs. However, many graphs used in these applications comprise millions of nodes and billio...
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Article
Open AccessOntologizing health systems data at scale: making translational discovery a reality
Common data models solve many challenges of standardizing electronic health record (EHR) data but are unable to semantically integrate all of the resources needed for deep phenoty**. Open Biological and Biom...
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Article
Open AccessUnifying the identification of biomedical entities with the Bioregistry
The standardized identification of biomedical entities is a cornerstone of interoperability, reuse, and data integration in the life sciences. Several registries have been developed to catalog resources mainta...
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Article
The GA4GH Phenopacket schema defines a computable representation of clinical data
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Article
Open AccessNSAID use and clinical outcomes in COVID-19 patients: a 38-center retrospective cohort study
Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly used to reduce pain, fever, and inflammation but have been associated with complications in community-acquired pneumonia. Observations shortly after ...
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Chapter and Conference Paper
Hypernetwork Science: From Multidimensional Networks to Computational Topology
As data and mathematical objects used for complex systems modeling, hypergraphs sit nicely poised between on the one hand the world of network models, and on the other that of higher-order mathematical abs...
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Article
Open AccessSemantic integration of clinical laboratory tests from electronic health records for deep phenoty** and biomarker discovery
Electronic Health Record (EHR) systems typically define laboratory test results using the Laboratory Observation Identifier Names and Codes (LOINC) and can transmit them using Fast Healthcare Interoperability ...
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Article
Relationships Between Marijuana Dependence and Condom Use Intentions and Behavior Among Justice-Involved Adolescents
The current study examined the relationships among marijuana dependence, a theoretical model of condom use intentions, and subsequent condom use behavior in justice-involved adolescents. Participants completed...