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  1. Article

    Open Access

    Association of post-COVID phenotypic manifestations with new-onset psychiatric disease

    Acute COVID-19 infection can be followed by diverse clinical manifestations referred to as Post Acute Sequelae of SARS-CoV2 Infection (PASC). Studies have shown an increased risk of being diagnosed with new-on...

    Ben Coleman, Elena Casiraghi, Tiffany J. Callahan, Hannah Blau in Translational Psychiatry (2024)

  2. Article

    Open Access

    An open source knowledge graph ecosystem for the life sciences

    Translational research requires data at multiple scales of biological organization. Advancements in sequencing and multi-omics technologies have increased the availability of these data, but researchers face s...

    Tiffany J. Callahan, Ignacio J. Tripodi, Adrianne L. Stefanski in Scientific Data (2024)

  3. Article

    Open Access

    GRAPE for fast and scalable graph processing and random-walk-based embedding

    Graph representation learning methods opened new avenues for addressing complex, real-world problems represented by graphs. However, many graphs used in these applications comprise millions of nodes and billio...

    Luca Cappelletti, Tommaso Fontana, Elena Casiraghi in Nature Computational Science (2023)

  4. Article

    Open Access

    Ontologizing health systems data at scale: making translational discovery a reality

    Common data models solve many challenges of standardizing electronic health record (EHR) data but are unable to semantically integrate all of the resources needed for deep phenoty**. Open Biological and Biom...

    Tiffany J. Callahan, Adrianne L. Stefanski, Jordan M. Wyrwa in npj Digital Medicine (2023)

  5. Article

    Open Access

    Unifying the identification of biomedical entities with the Bioregistry

    The standardized identification of biomedical entities is a cornerstone of interoperability, reuse, and data integration in the life sciences. Several registries have been developed to catalog resources mainta...

    Charles Tapley Hoyt, Meghan Balk, Tiffany J. Callahan in Scientific Data (2022)

  6. No Access

    Article

    The GA4GH Phenopacket schema defines a computable representation of clinical data

    Julius O. B. Jacobsen, Michael Baudis, Gareth S. Baynam in Nature Biotechnology (2022)

  7. Article

    Open Access

    NSAID use and clinical outcomes in COVID-19 patients: a 38-center retrospective cohort study

    Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly used to reduce pain, fever, and inflammation but have been associated with complications in community-acquired pneumonia. Observations shortly after ...

    Justin T. Reese, Ben Coleman, Lauren Chan, Hannah Blau in Virology Journal (2022)

  8. No Access

    Chapter and Conference Paper

    Hypernetwork Science: From Multidimensional Networks to Computational Topology

    As data  and mathematical objects used for complex systems modeling,  hypergraphs sit nicely poised between on the one hand the world of network models,  and on the other that of higher-order mathematical abs...

    Cliff A. Joslyn, Sinan G. Aksoy in Unifying Themes in Complex Systems X (2021)

  9. Article

    Open Access

    Semantic integration of clinical laboratory tests from electronic health records for deep phenoty** and biomarker discovery

    Electronic Health Record (EHR) systems typically define laboratory test results using the Laboratory Observation Identifier Names and Codes (LOINC) and can transmit them using Fast Healthcare Interoperability ...

    **ngmin Aaron Zhang, Amy Yates, Nicole Vasilevsky, J. P. Gourdine in npj Digital Medicine (2019)

  10. No Access

    Article

    Relationships Between Marijuana Dependence and Condom Use Intentions and Behavior Among Justice-Involved Adolescents

    The current study examined the relationships among marijuana dependence, a theoretical model of condom use intentions, and subsequent condom use behavior in justice-involved adolescents. Participants completed...

    Tiffany J. Callahan, Ann E. Caldwell Hooper, Rachel E. Thayer in AIDS and Behavior (2013)