-
Article
Biomonitoring of nickel and chromium in human pulmonary tissue
Nickel (Ni) and chromium (Cr) and some of its compounds may be able to induce cancer in the lungs as well as in the nose and paranasal sinuses after occupational exposure. Latency periods amount to 20 years an...
-
Article
Effects of Mixed ETA and ETB-Receptor Antagonist (Ro-47-0203) on Hepatic Microcirculation After Warm Ischemia
There is evidence that endothelin (ET) isinvolved in disturbances of the hepatic microcirculationafter warm ischemia. In this study we investigated theinfluence of a mixed ETA-,ETB-receptor antagonist (Bosentan) ...
-
Article
Characterization of the sigma ligand panamesine, a potential antipsychotic, by immune response in patients with schizophrenia and by sleep-EEG changes in normal controls
Panamesine (PAN) is a nearly specific sigma ligand. Recently, we showed that PAN in doses up to 90 mg/day improved psychometric variables in patients with an acute episode of schizophrenia. No side effects co...
-
Article
Sequential (domino) transplantation of the liver in a transthyretin-50 familial amyloid polyneuropathy
Background: General shortage of cadaveric organs has led to a search for alternative methods to expand the donor pool. Sequential (domino) transplantation is yet another attempt to compensate for the declining c...
-
Article
Schlaf und Schläfrigkeit im Rahmen von Infektionen und im Rahmen experimenteller Immunmodulation beim Menschen
Infektionen, Entzündungen und Autoimmunprozesse sind von erheblichen Störungen des Wohlbefindens, der beruflichen und sozialen Leistungsfähigkeit, der kognitiven Funktionen und des Verhaltens begleitet. Insbes...
-
Article
Characterization of Renal Parenchymal Perfusion during Experimental Infrarenal Aortic Clam** and Declam** with Enhanced Thermodiffusion Electrodes
-
Article
The impact of the Euro on the return structure of European equity markets
-
Chapter and Conference Paper
LiverLine — ein webbasiertes Informationssystem für die computergestützte Leberoperationsplanung
Die computergestützte Operationsplanung in der Leberchirurgie liefert eine dreidimensionale Rekonstruktion der Leber, welche die Lage des Tumors gegenüber den Gefäßbäumen und deren Versorgungsgebieten enthält....
-
Chapter and Conference Paper
Ein Bildverarbeitungssystem für die automatisierte Vermessung und quantitative Verlaufsdokumentation von pleuralen Verdickungen
Zur Früherkennung von Pleuramesotheliomen wurde ein Bild Verarbeitungssystem entwickelt, welches pleurale Verdickungen semiautomatisch lokalisiert, vermisst und dokumentiert. Durch den Vergleich der Befundungs...
-
Chapter
Coding CT-Classification in Occupational and Environmental Respiratory Disease (OERD)
-
Chapter and Conference Paper
3D-Erkennung, Analyse und Visualisierung pleuraler Verdickungen in CT-Daten
Aufbauend auf früheren Arbeiten wurde ein Bildverarbeitungssystem entwickelt, welches pleurale Verdickungen automatisch lokalisiert und visualisiert. Es liefert reproduzierbare, quantitative Daten, die eine ge...
-
Article
Open AccessAluminosis – Detection of an almost forgotten disease with HRCT
The aim of this study was to investigate whether it is possible to detect high-resolution computed tomography (HRCT) findings in aluminium powder workers, which are consistent with early stages of aluminosis.
-
Article
Open AccessMethod optimization and validation for the simultaneous determination of arachidonic acid metabolites in exhaled breath condensate by liquid chromatography-electrospray ionization tandem mass spectrometry
Determinations of inflammatory markers in exhaled breath condensate were used to assess airway inflammation. The most applied method for this kind of determination is enzyme immunoassay. For research purposes ...
-
Article
Open AccessAnalysing the causes of chronic cough: relation to diesel exhaust, ozone, nitrogen oxides, sulphur oxides and other environmental factors
Air pollution remains a leading cause of many respiratory diseases including chronic cough. Although episodes of incidental, dramatic air pollution are relatively rare, current levels of exposure of pollutants...
-
Article
Asbestos Surveillance Program Aachen (ASPA): initial results from baseline screening for lung cancer in asbestos-exposed high-risk individuals using low-dose multidetector-row CT
The purpose of this study was to assess the prevalence of lung cancer in a high-risk asbestos-exposed cohort using low-dose MDCT. Of a population of 5,389 former power-plant workers, 316 were characterized as ...
-
Article
Memantine Pharmacotherapy
Memantine plasma concentrations show considerable interindividual variability. High memantine plasma concentrations are associated with the occurrence of neuropsychiatric adverse effects such as confusion. The...
-
Article
Focal progression in patients with gastrointestinal stromal tumors after initial response to imatinib mesylate: a three-center-based study of 38 patients
This study aimed to investigate the outcome of patients with advanced gastrointestinal stromal tumors (GISTs) exhibiting focal disease progression during imatinib therapy, treated by surgical resection and ima...
-
Article
Die EU-Feinstaub-Richtlinie und das Herz: Wo stehen wir heute in Europa?
Mit Inkrafttreten der EU-Feinstaub-Richtlinie (1999/30/EG) rückte ein innereuropäischer Diskurs zwischen Grundlagenforschung, epidemiologischen Erkenntnissen und gesundheitspolitischen Aspekten zunehmend in da...
-
Chapter
Markenführung bei TNT — Ohne die Mitarbeiter läuft nichts!
Die Fallstudie „Markenführung bei TNT“ befasst sich mit den beiden Unternehmen TNT Express und TNT Innight. Obwohl beide zur TNT-Gruppe gehören, waren die Ausgangssituation und die Herausforderungen und somit ...
-
Article
Validity Assessment for the Results of Three Inflammatory Markers in Exhaled Breath Condensate: A Pilot Study
This study was initiated to assess the validity of eicosanoid determination in exhaled breath condensate by immunoassays. The results were compared to those obtained from liquid chromatographic methods with ma...
