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  1. Article

    Open Access

    HIV-1 Vpr combats the PU.1-driven antiviral response in primary human macrophages

    HIV-1 Vpr promotes efficient spread of HIV-1 from macrophages to T cells by transcriptionally downmodulating restriction factors that target HIV-1 Envelope protein (Env). Here we find that Vpr induces broad tr...

    Maria C. Virgilio, Barkha Ramnani, Thomas Chen in Nature Communications (2024)

  2. No Access

    Article

    On the Well-Posedness and Stability of Cubic and Quintic Nonlinear Schrödinger Systems on \(\mathbb {T}^3\)

    In this paper, we study cubic and quintic nonlinear Schrödinger systems on three-dimensional tori, with initial data in an adapted Hilbert space ...

    Thomas Chen, Amie Bowles Urban in Annales Henri Poincaré (2024)

  3. No Access

    Article

    On the Emergence of Quantum Boltzmann Fluctuation Dynamics near a Bose–Einstein Condensate

    In this work, we study the quantum fluctuation dynamics in a Bose gas on a torus \(\Lambda =(L{\mathbb {T}})^3\) ...

    Thomas Chen, Michael Hott in Journal of Statistical Physics (2023)

  4. No Access

    Chapter and Conference Paper

    Optimized CNN Model with Deep Convolutional GAN for Brain Tumor Detection

    Brain tumors are viewed as a deadly form of cancer. Early and precise detection of brain tumors is critical to tumor cure. Magnetic resonance imaging and computed tomography are two widely used methods of exam...

    Mure Vamsi Kalyan Reddy, Prithvi K. Murjani in Third Congress on Intelligent Systems (2023)

  5. Article

    Open Access

    The time-dependent Hartree–Fock–Bogoliubov equations for Bosons

    We introduce the map of dynamics of quantum Bose gases into dynamics of quasifree states, which we call the “nonlinear quasifree approximation”. We use this map to derive the time-dependent Hartree–Fock–Bogoli...

    Volker Bach, Sebastien Breteaux, Thomas Chen in Journal of Evolution Equations (2022)

  6. No Access

    Article

    Small Data Global Well-Posedness for a Boltzmann Equation via Bilinear Spacetime Estimates

    We provide a new analysis of the Boltzmann equation with a constant collision kernel in two space dimensions. The scaling-critical Lebesgue space is ...

    Thomas Chen, Ryan Denlinger, Nataša Pavlović in Archive for Rational Mechanics and Analysis (2021)

  7. No Access

    Article

    Local Well-Posedness for Boltzmann’s Equation and the Boltzmann Hierarchy via Wigner Transform

    We use the dispersive properties of the linear Schrödinger equation to prove local well-posedness results for the Boltzmann equation and the related Boltzmann hierarchy, set in the spatial domain ...

    Thomas Chen, Ryan Denlinger, Nataša Pavlović in Communications in Mathematical Physics (2019)

  8. No Access

    Article

    Application of Machine Learning in Perovskite Solar Cell Crystal Size Distribution Analysis

    This research automates edge detection for perovskite crystal grains using machine learning (ML). Once the edges of the crystal grains are located, a flood-fill algorithm can be used to find the distribution o...

    Thomas Chen, Yuchen Zhou, Miriam Rafailovich in MRS Advances (2019)

  9. No Access

    Article

    The Weak Coupling Limit for the Random Schrödinger Equation: The Average Wave Function

    We consider the Schrödinger equation with a time-independent weakly random potential of a strength \({\epsilon\ll 1}\) ...

    Thomas Chen, Tomasz Komorowski, Lenya Ryzhik in Archive for Rational Mechanics and Analysis (2018)

  10. No Access

    Chapter and Conference Paper

    Your Code Is My Code: Exploiting a Common Weakness in OAuth 2.0 Implementations

    Many millions of users routinely use their Google, Facebook and Microsoft accounts to log in to websites supporting OAuth 2.0-based single sign on. The security of OAuth 2.0 is therefore of critical importance...

    Wanpeng Li, Chris J. Mitchell, Thomas Chen in Security Protocols XXVI (2018)

  11. No Access

    Article

    Global Well-Posedness of the NLS System for Infinitely Many Fermions

    In this paper, we study the mean field quantum fluctuation dynamics for a system of infinitely many fermions with delta pair interactions in the vicinity of an equilibrium solution (the Fermi sea) at zero temp...

    Thomas Chen, Younghun Hong, Nataša Pavlović in Archive for Rational Mechanics and Analysis (2017)

  12. No Access

    Article

    On the Well-Posedness and Scattering for the Gross–Pitaevskii Hierarchy via Quantum de Finetti

    We prove the existence of scattering states for the defocusing cubic Gross–Pitaevskii (GP) hierarchy in \({\mathbb{R}^3}\) ...

    Thomas Chen, Christian Hainzl, Nataša Pavlović in Letters in Mathematical Physics (2014)

  13. Article

    Existence and Nonlinear Stability of Stationary States for the Semi-Relativistic Schrödinger-Poisson System

    We study the stationary states of the semi-relativistic Schrödinger-Poisson system in the repulsive (plasma physics) Coulomb case. In particular, we establish the existence and the nonlinear stability of a wid...

    Walid Abou Salem, Thomas Chen, Vitali Vougalter in Annales Henri Poincaré (2014)

  14. Article

    Derivation of the Cubic NLS and Gross–Pitaevskii Hierarchy from Manybody Dynamics in d = 3 Based on Spacetime Norms

    We derive the defocusing cubic Gross–Pitaevskii (GP) hierarchy in dimension d = 3, from an N-body Schrödinger equation describing a gas of interacting bosons in the GP scaling, in the limit N → ∞. The main result...

    Thomas Chen, Nataša Pavlović in Annales Henri Poincaré (2014)

  15. Article

    Effective Dynamics of an Electron Coupled to an External Potential in Non-relativistic QED

    In the framework of non-relativistic QED, we show that the renormalized mass of the electron (after having taken into account radiative corrections) appears as the kinematic mass in its response to an external...

    Volker Bach, Thomas Chen, Jérémy Faupin, Jürg Fröhlich in Annales Henri Poincaré (2013)

  16. No Access

    Article

    A Lower Bound on Blowup Rates for the 3D Incompressible Euler Equation and a Single Exponential Beale-Kato-Majda Type Estimate

    We prove a Beale-Kato-Majda type criterion for the loss of regularity for solutions of the incompressible Euler equations in $${H^{s}(...

    Thomas Chen, Nataša Pavlović in Communications in Mathematical Physics (2012)

  17. No Access

    Article

    Targeted blue nanoparticles as photoacoustic contrast agent for brain tumor delineation

    Distinguishing a tumor from non-neoplastic tissue is a challenging task during cancer surgery. Several attempts have been made to use visible or fluorescent agents to aid in the visualization of a tumor during...

    Aniruddha Ray, Xueding Wang, Yong-Eun Koo Lee, Hoe ** Hah, Gwangseong Kim in Nano Research (2011)

  18. No Access

    Article

    Phase 1/pharmacology study of intraperitoneal topotecan alone and with cisplatin: potential for consolidation in ovarian cancer

    Most ovarian cancers recur after first-line treatment. We studied the pharmacology, tolerability, and therapeutic potential of intraperitoneal (IP) topotecan, alone and with IP cisplatin.

    Eleni Andreopoulou, Thomas Chen, Leonard Liebes in Cancer Chemotherapy and Pharmacology (2011)

  19. No Access

    Article

    Boltzmann Limit for a Homogeneous Fermi Gas with Dynamical Hartree-Fock Interactions in a Random Medium

    We study the dynamics of the thermal momentum distribution function for an interacting, homogeneous Fermi gas on ℤ3 in the presence of an external weak static random potential, where the pair interactions between...

    Thomas Chen, Igor Rodnianski in Journal of Statistical Physics (2011)

  20. No Access

    Chapter

    A Technical Description of the Brain Tumor Window Model: An In Vivo Model for the Evaluation of Intraoperative Contrast Agents

    The evaluation of candidate optical contrast agents for brain tumor delineation in ex vivo models may not accurately predict their activity in vivo. This study describes an in vivo model system designed to ass...

    Daniel A. Orringer, Thomas Chen, Dah-Luen Huang, Martin Philbert in Intraoperative Imaging (2011)

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