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  1. Article

    Open Access

    Between hope and reality: treatment of genetic diseases through nucleic acid-based drugs

    Rare diseases (RD) affect a small number of people compared to the general population and are mostly genetic in origin. The first clinical signs often appear at birth or in childhood, and patients endure high ...

    Virginie Baylot, Thi Khanh Le, David Taïeb, Palma Rocchi in Communications Biology (2024)

  2. Article

    Open Access

    Menin inhibition suppresses castration-resistant prostate cancer and enhances chemosensitivity

    Disease progression and therapeutic resistance of prostate cancer (PC) are linked to multiple molecular events that promote survival and plasticity. We previously showed that heat shock protein 27 (HSP27) acte...

    Chaïma Cherif, Dang Tan Nguyen, Clément Paris, Thi Khanh Le, Thibaud Sefiane in Oncogene (2022)