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  1. Article

    Open Access

    Survival associated pathway identification with group L p penalized global AUC maximization

    It has been demonstrated that genes in a cell do not act independently. They interact with one another to complete certain biological processes or to implement certain molecular functions. How to incorporate b...

    Zhenqiu Liu, Laurence S Magder, Terry Hyslop, Li Mao in Algorithms for Molecular Biology (2010)

  2. Article

    Open Access

    Selection of optimal reference genes for normalization in quantitative RT-PCR

    Normalization in real-time qRT-PCR is necessary to compensate for experimental variation. A popular normalization strategy employs reference gene(s), which may introduce additional variability into normalized ...

    Inna Chervoneva, Yanyan Li, Stephanie Schulz, Sean Croker in BMC Bioinformatics (2010)

  3. Article

    Open Access

    Revealing genes associated with vitellogenesis in the liver of the zebrafish (Danio rerio) by transcriptome profiling

    In oviparous vertebrates, including fish, vitellogenesis consists of highly regulated pathways involving 17β-estradiol (E2). Previous studies focused on a relatively small number of hepatic expressed genes dur...

    Liraz Levi, Irena Pekarski, Ellen Gutman, Paolo Fortina, Terry Hyslop in BMC Genomics (2009)