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  1. No Access

    Article

    Suppression of the malignant phenotype of human glioma cells by overexpression of manganese superoxide dismutase

    Manganese superoxide dismutase (MnSOD) has been previously shown to suppress the malignant phenotype of human melanoma and breast cancer cells. To test the possible role of MnSOD in glioma malignancy, MnSOD wa...

    Weixiong Zhong, Larry W Oberley, Terry D Oberley, Daret K St Clair in Oncogene (1997)

  2. No Access

    Article

    Manganese superoxide dismutase deficiency enhances cell turnover via tumor promoter-induced alterations in AP-1 and p53-mediated pathways in a skin cancer model

    Previous studies in our laboratories demonstrated that overexpression of manganese superoxide dismutase (MnSOD) suppressed both the incidence and multiplicity of papillomas in a DMBA/TPA multi-stage skin carci...

    Yunfent Zhao, Terry D Oberley, Luksana Chaiswing, Shu-mei Lin… in Oncogene (2002)

  3. No Access

    Article

    Increased manganese superoxide dismutase (SOD-2) is part of the mechanism for prostate tumor suppression by Mac25/insulin-like growth factor binding-protein-related protein-1

    Increased expression of mac25/insulin-like growth factor binding-protein related protein-1 (IGFBP-rP1) in human breast and prostate epithelial cell lines results in the suppression of tumor growth. CDNA expres...

    Stephen R Plymate, Kathy H Haugk, Cynthia C Sprenger, Peter S Nelson… in Oncogene (2003)

  4. No Access

    Article

    CuZnSOD deficiency leads to persistent and widespread oxidative damage and hepatocarcinogenesis later in life

    Mice deficient in CuZn superoxide dismutase (CuZnSOD) showed no overt abnormalities during development and early adulthood, but had a reduced lifespan and increased incidence of neoplastic changes in the liver...

    Sailaja Elchuri, Terry D Oberley, Wenbo Qi, Richard S Eisenstein… in Oncogene (2005)