Skip to main content

1 Result(s)

within Teresa Poggio Remove this filter Science, Humanities and Social Sciences, multidisciplinary Remove this filter

and

  1. No Access

    Article

    Phosphatidylinositol 3-kinase δ blockade increases genomic instability in B cells

    PI3Kδ controls the expression of the recombinogenic enzyme AID; excessive AID activity caused by PI3Kδ inhibition can induce genomic instability in leukaemia and lymphoma cells, as well as in patients with chr...

    Mara Compagno, Qi Wang, Chiara Pighi, Taek-Chin Cheong, Fei-Long Meng… in Nature (2017)