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  1. No Access

    Article

    Novel individualized power training protocol preserves physical function in adult and older mice

    Sarcopenia, the age-related loss of muscle mass and strength, contributes to frailty, functional decline, and reduced quality of life in older adults. Exercise is a recognized therapy for sarcopenia and muscle...

    Ted G. Graber, Katie R. Fandrey, LaDora V. Thompson in GeroScience (2019)

  2. Article

    Open Access

    Essential amino acid ingestion alters expression of genes associated with amino acid sensing, transport, and mTORC1 regulation in human skeletal muscle

    Amino acid availability stimulates protein synthesis via the mTORC1 (mechanistic target of rapamycin complex 1) signaling pathway. In response to an increase in cellular amino acid availability, translocation ...

    Ted G. Graber, Michael S. Borack, Paul T. Reidy, Elena Volpi… in Nutrition & Metabolism (2017)

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  3. Article

    Open Access

    C57BL/6 life span study: age-related declines in muscle power production and contractile velocity

    Quantification of key outcome measures in animal models of aging is an important step preceding intervention testing. One such measurement, skeletal muscle power generation (force * velocity), is critical for ...

    Ted G. Graber, Jong-Hee Kim, Robert W. Grange, Linda K. McLoon, LaDora V. Thompson in AGE (2015)

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  4. No Access

    Article

    Immunoproteasome in animal models of Duchenne muscular dystrophy

    Increased proteasome activity has been implicated in the atrophy and deterioration associated with dystrophic muscles of Duchenne muscular dystrophy (DMD). While proteasome inhibitors show promise in the atte...

    Chiao-nan Joyce Chen, Ted G. Graber… in Journal of Muscle Research and Cell Motili… (2014)