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  1. Article

    Open Access

    Association between intrapleural urokinase monotherapy and treatment failure in patients with pleural infection: a retrospective cohort study

    Pleural infection, an infection of the pleural space, is frequently treated with antibiotics and thoracic tube drainage. In case of insufficient drainage, an intrapleural fibrinolytic agent is considered befor...

    Jumpei Taniguchi, Hiroki Matsui, Tatsuya Nagai, Ayumu Otsuki in BMC Pulmonary Medicine (2023)

  2. Article

    Open Access

    Alterations of auditory-evoked gamma oscillations are more pronounced than alterations of spontaneous power of gamma oscillation in early stages of schizophrenia

    Several animal models of schizophrenia and patients with chronic schizophrenia have shown increased spontaneous power of gamma oscillations. However, the most robust alterations of gamma oscillations in patien...

    Mariko Tada, Kenji Kirihara, Daisuke Koshiyama, Tatsuya Nagai in Translational Psychiatry (2023)

  3. Article

    Open Access

    Optical coherence tomography findings in three patients with Werner syndrome

    Werner syndrome is a rare, autosomal recessive disorder characterised by premature aging. It is a typical hereditary progeroid syndrome that can be difficult to diagnose owing to its rarity and the similarity ...

    Tatsuya Nagai, Hirotaka Yokouchi, Gen Miura, Masaya Koshizaka in BMC Ophthalmology (2022)

  4. Article

    Open Access

    The relationship between chest tube position in the thoracic cavity and treatment failure in patients with pleural infection: a retrospective cohort study

    Pleural infection is an infection of the pleural space that is usually treated with antibiotics and source control. Chest tube insertion is the most popular and widely used drainage technique. We typically att...

    Jumpei Taniguchi, Kei Nakashima, Hiroki Matsui, Tatsuya Nagai in BMC Pulmonary Medicine (2022)

  5. Article

    Open Access

    Development of plasmonic thin-layer chromatography for size-selective and optical-property-dependent separation of quantum dots

    Nano-objects, such as quantum dots (QDs), are essential units for the construction of functional materials and devices in current technologies. The establishment of a versatile scheme to sort desired component...

    Tsukasa Torimoto, Naoko Yamaguchi, Yui Maeda, Kazutaka Akiyoshi in NPG Asia Materials (2022)

  6. Article

    Open Access

    Corticosteroids for hospitalized patients with mild to critically-ill COVID-19: a multicenter, retrospective, propensity score-matched study

    Corticosteroids use in coronavirus disease 2019 (COVID-19) is controversial, especially in mild to severe patients who do not require invasive/noninvasive ventilation. Moreover, many factors remain unclear reg...

    Satoshi Ikeda, Toshihiro Misumi, Shinyu Izumi, Keita Sakamoto in Scientific Reports (2021)

  7. Article

    Open Access

    Electrophysiological evidence for abnormal glutamate-GABA association following psychosis onset

    Previous studies have shown glutamatergic dysfunction and γ-aminobutyric acid (GABA)-ergic dysfunction in schizophrenia. Animal studies suggest that N-methyl-d-aspartate receptor (NMDAR) dysfunction and GABA-ergi...

    Daisuke Koshiyama, Kenji Kirihara, Mariko Tada, Tatsuya Nagai in Translational Psychiatry (2018)

  8. No Access

    Article

    Anatomical integration of the sacral–hindlimb unit coordinated by GDF11 underlies variation in hindlimb positioning in tetrapods

    Elucidating how body parts from different primordia are integrated during development is essential for understanding the nature of morphological evolution. In tetrapod evolution, while the position of the hind...

    Yoshiyuki Matsubara, Tatsuya Hirasawa, Shiro Egawa in Nature Ecology & Evolution (2017)

  9. Article

    Open Access

    Reduced Mismatch Negativity is Associated with Increased Plasma Level of Glutamate in First-episode Psychosis

    Reduced amplitude of mismatch negativity (MMN) is one of the more promising biological markers of schizophrenia. This finding holds true in both early and chronic phases of the disorder, and is compatible with...

    Tatsuya Nagai, Kenji Kirihara, Mariko Tada, Daisuke Koshiyama in Scientific Reports (2017)

  10. No Access

    Chapter

    Gasless Single-Port RoboSurgeon Retroperitoneoscopic Partial Nephrectomy

    Gasless single-port RoboSurgeon clampless sutureless partial nephrectomy is performed for a wide range of renal tumors. It is an affordable procedure for patients with renal cell carcinoma and is carried out i...

    Kazunori Kihara, Yasuhisa Fujii in Gasless Single-Port RoboSurgeon Surgery in… (2015)

  11. No Access

    Article

    Pure pressure stress increased monocarboxylate transporter in human aortic smooth muscle cell membrane

    Lactate is formed and utilized continuously under fully aerobic conditions. Lactate is oxidized actively at all times, especially during exercise. Family of monocarboxylate transport proteins (MCTs) that are d...

    Koji Oikawa, Kenji Iizuka, Takeshi Murakami in Molecular and Cellular Biochemistry (2004)

  12. No Access

    Article

    A 44-kDa of protein identical to the N-terminal amino acid sequence of MCT1 in human circulation

    A family of specific carrier protein designated as monocarboxylate transporter (MCT) has been known to transport the lactate and other moncarboxylates in mammalian cells. We hypothesized the presence of serum ...

    Kenji Iizuka, Noriteru Morita, Tatsuya Nagai in Molecular and Cellular Biochemistry (2003)