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    Increased C-CRK proto-oncogene expression is associated with an aggressive phenotype in lung adenocarcinomas

    The C-CRK gene, cellular homolog of the avian v-crk oncogene, encodes two alternatively spliced adaptor signaling proteins, CRKI (28 kDa) and CRKII (40 kDa). Both CRKI and CRKII have been shown to activate kinase...

    Charles T Miller, Guoan Chen, Tarek G Gharib, Hong Wang, Dafydd G Thomas… in Oncogene (2003)