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  1. No Access

    Article

    Increased C-CRK proto-oncogene expression is associated with an aggressive phenotype in lung adenocarcinomas

    The C-CRK gene, cellular homolog of the avian v-crk oncogene, encodes two alternatively spliced adaptor signaling proteins, CRKI (28 kDa) and CRKII (40 kDa). Both CRKI and CRKII have been shown to activate kinase...

    Charles T Miller, Guoan Chen, Tarek G Gharib, Hong Wang, Dafydd G Thomas… in Oncogene (2003)

  2. No Access

    Article

    Gene-expression profiles predict survival of patients with lung adenocarcinoma

    Histopathology is insufficient to predict disease progression and clinical outcome in lung adenocarcinoma. Here we show that gene-expression profiles based on microarray analysis can be used to predict patient...

    David G. Beer, Sharon L.R. Kardia, Chiang-Ching Huang… in Nature Medicine (2002)