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Article
Contamination source modeling with SCRuB improves cancer phenotype prediction from microbiome data
Sequencing-based approaches for the analysis of microbial communities are susceptible to contamination, which could mask biological signals or generate artifactual ones. Methods for in silico decontamination u...
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Article
Open AccessImpact of diet and host genetics on the murine intestinal mycobiome
The mammalian gut is home to a diverse microbial ecosystem, whose composition affects various physiological traits of the host. Next-generation sequencing-based metagenomic approaches demonstrated how the inte...
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Article
Open AccessGene-diet interactions associated with complex trait variation in an advanced intercross outbred mouse line
Phenotypic variation of quantitative traits is orchestrated by a complex interplay between the environment (e.g. diet) and genetics. However, the impact of gene-environment interactions on phenotypic traits mo...
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Article
Open AccessDissecting genetics of cutaneous miRNA in a mouse model of an autoimmune blistering disease
MicroRNAs (miRNAs) are small endogenous non-coding RNAs that control genes at post-transcriptional level. They are essential for development and tissue differentiation, and such altered miRNA expression patterns ...
