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Article
Open AccessAcute osteomyelitis, thrombophlebitis, and pulmonary embolism: a case report
Septic pulmonary embolism (SPE), deep vein thrombophlebitis (DVT), and acute osteomyelitis (AOM) form a triad that is rarely seen in children and is usually associated with a history of trauma on long bones. U...
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Article
Autologous hematopoietic cell transplantation as a part of a sequential multi-phase therapeutic approach (R-COPADM/CYVE/ASCT) as first-line treatment of high-grade B-cell lymphoma: results of a retrospective study with long-term follow-up
Patients with high-risk lymphoma have a poor prognosis when treated with standard chemoimmunotherapy. This retrospective study included 23 high-risk lymphoma patients with a median age at diagnosis of 59 (rang...
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Article
Nilotinib efficacy and safety as salvage treatment following imatinib intolerance and/or inefficacy in steroid refractory chronic graft-versus-host-disease (SR-cGVHD): a prospective, multicenter, phase II study on behalf of the Francophone Society of Bone Marrow Transplantation and Cellular Therapy (SFGM-TC)
Imatinib is used for patients with SR-cGVHD. However, in 50% of cases imatinib is discontinued due to intolerance or inefficacy. In order to investigate nilotinib’s role as salvage therapy in those patients, w...
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Article
Tixagevimab/cilgavimab for Omicron SARS-CoV-2 infection in patients with haematologic diseases
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Article
Open AccessSuccessful management of ectopic kidney stones in a patient with situs inversus totalis: a rare case report
Situs inversus totalis is a very rare congenital anatomical variation, in which all thoracic and abdominal organs are right-left inverted. This condition is associated with an increased risk of organ malformat...
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Article
Open AccessFibromyalgia: epidemiology and risk factors, a population-based case-control study in Damascus, Syria
Fibromyalgia is a chronic disease with a high burden. We aim to be the first to investigate the prevalence of fibromyalgia (FM) in Syria and assess its risk factors.
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Article
Open AccessChondral delamination of the knee and its management: a case report and review article
Chondral delamination is the separation or debonding of the articular cartilage from the underlying subchondral bone. The hyaline cartilage has a limited capacity for healing, meaning it does not possess the i...
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Article
Open AccessPrimary psoas tuberculosis abscess with an iliac bone lytic lesion: a case report
Primary psoas tuberculosis is the presence of “Koch’s bacillus’’ within the iliopsoas muscle caused by hematogenous or lymphatic seeding from a distant site. Muscular tuberculosis has relatively low prevalence...
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Article
Open AccessSmall bowel diverticula in elderly patients: a case report and review article
Small intestine diverticula are rare findings that were mostly reported in the elderly population as asymptomatic findings. However, they can also present with a wide range of symptoms (bloating, early satiety...
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Article
Open AccessMultiple vas deferens with polyorchidism and many congenital malformations in a symptomatic 11-year-old male patient: a rare case report
Ductus deferens may manifest in a variety of anomalies such as its absence, duplication, ectopy, or diverticulum. Ectopic seminal tract opening has two main types, ectopic ejaculatory duct opening, and ectopic...
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Article
Open AccessA 35-year-old father with persistent Mullerian duct syndrome and seminoma of the right undescended testis: a rare case report
A persistent Müllerian duct syndrome is a rare disorder of sexual differentiation characterized by the presence of the female reproductive system in a normal male.
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Article
Privacy preservation of genome data analysis using homomorphic encryption
Very few organizations can afford the necessary infrastructure for genomic data analytic, which requires a very large amount of storage and computational resources. In this context, cloud computing platforms c...
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Article
Open AccessCOVID-19 vaccination acceptance among Syrian population: a nationwide cross-sectional study
Severe Acute Respiratory Syndrome Coronavirus 2 continues to spread globally and in the absence of an effective treatment, the vaccine remains the best hope for controlling this disease. In this study, we seek...
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Article
Open AccessLanguage of written medical educational materials for non-English speaking populations: an evaluation of a simplified bi-lingual approach
Debates have arisen in various non-English speaking countries over the chosen language of instruction in medical education, whether it has to be the English language or the mother tongue. English-based educati...
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Article
Donor-derived CD4+/CCR7+ T-cell impact on acute GVHD incidence following haplo-HCT after reduced intensity conditioning and posttransplant cyclophosphamide
In previous studies, we and others observed in patients undergoing HLA-matched hematopoietic cell transplantation that high proportion of donor-derived CD4+/CCR7+ T cells were associated with an increased risk of...
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Article
Cytotect®CP as salvage therapy in patients with CMV infection following allogeneic hematopoietic cell transplantation: a multicenter retrospective study
Cytomegalovirus is one of the main contributing factors to high mortality rates in patients undergoing allogeneic hematopoietic cell transplantation (allo-HCT). The main factors of treatment failure are both d...
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Article
Open AccessDurable Resolution of Severe Psoriasis in a Patient Treated with Pentostatin for Hairy Cell Leukemia: A Case Report
Pentostatin (2′-deoxycoformycin) and cladribine (2-chlorodeoxyadenosine) are adenosine analogues widely used to treat lymphoid malignancies, mainly hairy cell leukemia (HCL). Oral or parenteral adenosine analo...
