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Article
Deep learning model to predict Ki-67 expression of breast cancer using digital breast tomosynthesis
Develo** a deep learning (DL) model for digital breast tomosynthesis (DBT) images to predict Ki-67 expression.
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Article
Postoperative management using a digital drainage system for massive air leakage after pulmonary resection
To elucidate clinical outcomes using a digital drainage system (DDS) for massive air leakage (MAL) after pulmonary resection.
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Article
Open AccessIntensive care unit mortality and cost-effectiveness associated with intensivist staffing: a Japanese nationwide observational study
Japan has four types of intensive care units (ICUs) that are divided into two categories according to the management fee charged per day: ICU management fees 1 and 2 (ICU1/2) (equivalent to high-intensity staf...
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Article
Deep learning model for predicting the presence of stromal invasion of breast cancer on digital breast tomosynthesis
To develop a deep learning (DL)-based algorithm to predict the presence of stromal invasion in breast cancer using digital breast tomosynthesis (DBT). Our institutional review board approved this retrospective...
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Article
Deep learning model for breast cancer diagnosis based on bilateral asymmetrical detection (BilAD) in digital breast tomosynthesis images
The purpose of this study was to develop a deep learning model to diagnose breast cancer by embedding a diagnostic algorithm that examines the asymmetry of bilateral breast tissue. This retrospective study was...
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Article
Open AccessSignificance of systolic-phase imaging on full-phase ECG-gated CT angiography to detect intimal tears in aortic dissection
For patients with aortic dissection (AD) and intramural hematoma (IMH), the optimal cardiac phase to detect intimal tears (IT) and ulcer-like projections (ULP) on retrospective electrocardiogram (ECG)-gated co...
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Article
Open AccessSystemic-pulmonary collateral supply associated with clinical severity of chronic thromboembolic pulmonary hypertension: a study using intra-aortic computed tomography angiography
To assess whether systemic-pulmonary collaterals are associated with clinical severity and extent of pulmonary perfusion defects in chronic thromboembolic pulmonary hypertension (CTEPH).
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Chapter and Conference Paper
Numerical Study for Blood Flows in Thoracic Aorta
Numerical simulations for blood flows related to cardiovascular diseases are presented. Differences in vessel morphologies produce different flow characteristics, stress distributions, and ultimately different...
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Article
Open AccessDetection of the intimal tear in aortic dissection and ulcer-like projection in intramural hematoma: usefulness of full-phase retrospective ECG-gated CT angiography
To compare the accuracy of non-electrocardiogram (ECG)-gated CT angiography (CTA), single-diastolic-phase ECG-gated CTA, and full-phase ECG-gated CTA in detecting the intimal tear (IT) in aortic dissection (AD...
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Article
Open AccessThe level of antimicrobial resistance of sewage isolates is higher than that of river isolates in different Escherichia coli lineages
The dissemination of antimicrobial-resistant bacteria in environmental water is an emerging concern in medical and industrial settings. Here, we analysed the antimicrobial resistance of Escherichia coli isolates ...
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Article
Open AccessReconstituted cell-free protein synthesis using in vitro transcribed tRNAs
Entire reconstitution of tRNAs for active protein production in a cell-free system brings flexibility into the genetic code engineering. It can also contribute to the field of cell-free synthetic biology, whic...
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Article
Delayed cut-end recurrence after wedge resection for pulmonary ground-glass opacity adenocarcinoma despite negative surgical margin
Most pulmonary ground-glass opacity (GGO) nodules are pathologically well differentiated adenocarcinomas. We performed a limited resection trial of GGO lesions 2 cm or smaller from 2003 to 2009, in which 95 pa...
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Article
Open AccessIn vitro reconstitution of functional small ribosomal subunit assembly for comprehensive analysis of ribosomal elements in E. coli
In vitro reconstitution is a powerful tool for investigating ribosome functions and biogenesis, as well as discovering new ribosomal features. In this study, we integrated all of the processes required for Escher...
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Article
Open AccessArtificial photosynthetic cell producing energy for protein synthesis
Attempts to construct an artificial cell have widened our understanding of living organisms. Many intracellular systems have been reconstructed by assembling molecules, however the mechanism to synthesize its ...
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Article
Open AccessCdsA is involved in biosynthesis of glycolipid MPIase essential for membrane protein integration in vivo
MPIase is a glycolipid that is involved in membrane protein integration. Despite evaluation of its functions in vitro, the lack of information on MPIase biosynthesis hampered verification of its involvement in vi...
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Article
Construction of integrated gene logic-chip
In synthetic biology, the control of gene expression requires a multistep processing of biological signals. The key steps are sensing the environment, computing information and outputting products1. To achieve su...
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Article
Immunosuppressive tumor microenvironment of usual interstitial pneumonia-associated squamous cell carcinoma of the lung
Patients with usual interstitial pneumonia (UIP) often develop lung cancer. However, the biological features of lung cancer associated with UIP remain unknown. The aim of this study was to elucidate the clinic...
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Article
Correction to: Postoperative atrial fibrillation is less frequent in pulmonary segmentectomy compared with lobectomy
In the original publication of this article, the Table 1 was published incorrectly with missing data.
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Article
Postoperative atrial fibrillation is less frequent in pulmonary segmentectomy compared with lobectomy
The aim of this study was to elucidate the characteristics and predictors of postoperative atrial fibrillation (POAF) from the standpoint of surgical mode.
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Article
Open AccessLarge-scale aggregation analysis of eukaryotic proteins reveals an involvement of intrinsically disordered regions in protein folding
A subset of the proteome is prone to aggregate formation, which is prevented by chaperones in the cell. To investigate whether the basic principle underlying the aggregation process is common in prokaryotes an...
